~7 spots leftby Apr 2026

Clinical Trial of Wireless CranioFacial Nerve Stimulation (CFNS) for the Treatment of CranioFacial Neuropathic Pain

Recruiting in Palo Alto (17 mi)
+6 other locations
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: Curonix LLC
No Placebo Group

Trial Summary

What is the purpose of this trial?

The purpose of this study is to assess the effectiveness of craniofacial nerve stimulation for the treatment of neuropathic pain.

Research Team

Eligibility Criteria

Inclusion Criteria

Subject is ≥ 18 years of age at time of informed consent
Subjects have been diagnosed with Cranial-facial pain with an average VAS > 5 (on a 0-10 scale) over the course of the last month based on baseline pain diary.
No medication overuse and not attributed to another causative disorder
See 7 more

Treatment Details

Interventions

  • Halo Craniofacial Nerve Stimulator System (Neurostimulation Device)
Participant Groups
2Treatment groups
Experimental Treatment
Active Control
Group I: Continued Stimulation GroupExperimental Treatment1 Intervention
Subjects randomized to this group will have the Halo Craniofacial Nerve Stimulator System activated immediately.
Group II: Delayed Continuation GroupActive Control1 Intervention
Subjects randomized to this group with have the Halo Craniofacial Nerve Stimulator System activated after 90 days.

Find a Clinic Near You

Research Locations NearbySelect from list below to view details:
International Spine, Pain & Performance CenterWashington, United States
Goodman Campbell Brain and Spine, Indiana UniversityIndianapolis, IN
Prizm Pain ManagementCanton, MI
Minimally Invasive Pain InstituteUtica, NY
More Trial Locations
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Who Is Running the Clinical Trial?

Curonix LLC

Lead Sponsor

Trials
9
Patients Recruited
680+

Stimwave Technologies

Lead Sponsor

Trials
7
Patients Recruited
440+

Baylor College of Medicine

Collaborator

Trials
1044
Patients Recruited
6,031,000+

Pennsylvania Hospital, Philadelphia, Pennsylvania, USA

Collaborator

Trials
1
Patients Recruited
60+

Prizm Pain Management, Canton, Michigan

Collaborator

Trials
1
Patients Recruited
60+

Minimally Invasive Pain Institute, Utica, New York, USA

Collaborator

Trials
1
Patients Recruited
60+

Case Western Reserve University, Cleveland, Ohio, USA

Collaborator

Trials
1
Patients Recruited
60+

Goodman Campbell Brain and Spine, Indiana University, Indianapolis, Indiana, USA

Collaborator

Trials
1
Patients Recruited
60+

International Spine, Pain and Performance Center, Washington DC, USA

Collaborator

Trials
1
Patients Recruited
60+