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Dietary Fatty Acid Profiles for Type 2 Diabetes (METAc Trial)

N/A

Recruiting

Led By Alain Veilleux, PhD

Research Sponsored by Laval University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Men and women aged between 45 and 65 years, menopaused women

Men and women aged between 45 and 65 years, menopaused women ;

Must not have

Type 1 diabetes or insulin-treated diabetes

Intestinal pathologies including inflammatory bowel disease and gastrointestinal cancers

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 7 days

Awards & highlights

No Placebo-Only Group

Summary

This trial looks at how fatty acids affect the body's production of dietary metabolites in people with and without obesity and T2D.

Who is the study for?

This trial is for men and women aged 45-65, with a BMI of 20-35 kg/m², who are generally healthy and have a moderate diet quality. They must understand French and have internet access. It's not for smokers, heavy drinkers, recent antibiotic users, those on omega-3 supplements or with significant weight changes recently.

What is being tested?

The study looks at how different types of fats in meals (saturated vs. polyunsaturated fatty acids) affect the production of certain metabolites by gut bacteria in people with/without obesity and Type 2 diabetes.

What are the potential side effects?

Since this is a nutritional intervention focusing on meal content rather than medication or invasive procedures, side effects may be minimal but could include digestive discomfort depending on individual reactions to dietary fat changes.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am between 45 and 65 years old, or I am a woman who has gone through menopause.

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I am between 45 and 65 years old, or I am a woman who has gone through menopause.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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I have type 1 diabetes or use insulin for my diabetes.

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I have a condition affecting my intestines, like IBD or gastrointestinal cancer.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 7 days

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~7 days

This trial's timeline: 3 weeks for screening, Varies for treatment, and 7 days for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Fasting and postprandial lipid metabolite production in response to dietary lipid intervention in abdominal obesity and type 2 diabetes

Secondary study objectives

Gut microbiota in response to a 2 day dietary lipid intervention in abdominal obesity and type 2 diabetes

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: SingleExperimental Treatment1 Intervention

All participating subjects will undergo 3 feeding phases : 3 days of a run-in diet, 2 days of a polyunsaturated fatty acid (PUFA) diet and 2 days of a saturated fatty acid (SFA) diet.

0 / 4Eligibility criteria met