Measuring Automated Behavioral Observations & Vocal Expressions (ABOVE)
(ABOVE Trial)

Recruiting in Palo Alto (17 mi)

+2 other locations

Overseen byWayne Goodman, MD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Baylor College of Medicine

No Placebo Group

Trial Summary

What is the purpose of this trial?The investigators propose to synchronize automated measurements of behavior - head, body, and face dynamics, gaze, and vocal prosody - with simultaneous recordings of brain activity in clinically relevant contexts.

Eligibility Criteria

Inclusion Criteria

The subject has a minimum score of ≥16 on the Y-BOCS;

If applicable, on a stable pharmacologic regimen;

Sample will be enriched with OCD subjects having contamination obsessions and handwashing compulsions, and scores on items 9 and 10 of the Y-BOCS reflecting difficulty resisting and controlling compulsions;

+3 more

Participant Groups

2Treatment groups

Experimental Treatment

Group I: OCD subjectsExperimental Treatment3 Interventions

Subjects meeting inclusion/exclusion criteria with OCD will be exposed to the following: * Provocation OC task (Provoc) * Trier Social Stress Test (TSST) * Exposure provocation task

Group II: Control subjectsExperimental Treatment3 Interventions

Subjects meeting inclusion/exclusion criteria without OCD (age and gender matched with OCD subjects) will be exposed to the following: * Provocation OC task (Provoc) * Trier Social Stress Test (TSST) * Exposure provocation task