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Behavioral Intervention
Exposure Therapy for OCD
N/A
Recruiting
Led By Jennie M Kuckertz, PhD
Research Sponsored by Mclean Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Between the ages of 18-65 years old
Have a diagnosis of OCD
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 12 weeks
Awards & highlights
No Placebo-Only Group
Summary
"This trial aims to understand why some patients with Obsessive Compulsive Disorder (OCD) do not fully recover with exposure therapy. The study will involve 400 adult participants receiving exposure therapy from two
Who is the study for?
This trial is for adults aged 18-65 with Obsessive Compulsive Disorder (OCD) who are seeking exposure therapy at McLean Hospital OCD Institute or San Diego State University. Participants must be able to complete study measures and treatment procedures in English.
What is being tested?
The study aims to identify key mechanisms that make exposure therapy effective for treating OCD by analyzing self-reported data, observer-rated behavior, and physiological responses like heart rate during therapy sessions.
What are the potential side effects?
Exposure therapy typically does not involve medication, so traditional side effects are minimal. However, it can temporarily increase anxiety levels as patients confront their fears.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I am between 18 and 65 years old.
Select...
I have been diagnosed with OCD.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ up to 12 weeks
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 12 weeks
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Yale-Brown Obsessive Compulsive Scale (YBOCS)
Secondary study objectives
Quality of Life Enjoyment & Satisfaction Questionnaire (QLES)
Awards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Trial Design
1Treatment groups
Experimental Treatment
Group I: Exposure therapyExperimental Treatment1 Intervention
Participants will complete exposure therapy for up to 12 weeks, and each coached exposure session will be approximately 50 minutes. Exposure plans will be developed collaboratively between participants and their clinician at the beginning of treatment, and refined iteratively as clinically appropriate. In each coached exposure, participants will:
1. Complete an Exposure Feedback Form
2. Wear a wristwatch that provides psychophysiological data
The intervention will occur across two study sites (McLean Hospital, San Diego State University). Sites will differ on level of care. At McLean Hospital, participants will be recruited from the OCD Institute and will receive exposure therapy via partial hospital or residential setting as part of their standard care, regardless of participation in the study. At San Diego State University, participants will be recruited to receive exposure therapy via outpatient setting.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Exposure therapy
2012
N/A
~190
Find a Location
Who is running the clinical trial?
Mclean HospitalLead Sponsor
217 Previous Clinical Trials
21,793 Total Patients Enrolled
9 Trials studying Obsessive-Compulsive Disorder
307 Patients Enrolled for Obsessive-Compulsive Disorder
Jennie M Kuckertz, PhDPrincipal InvestigatorMclean Hospital