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Probiotic

The Effects of an Oral Probiotic Intervention With or Without a Novel ADP-1 Toothpaste

N/A
Waitlist Available
Research Sponsored by USANA Health Sciences
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 8 weeks

Summary

This trial tests if taking beneficial bacteria by mouth and using a new type of toothpaste can improve oral health better than regular toothpaste.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~8 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 8 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Gingival Index
Plaque Index
Secondary study objectives
Halitosis
Electrogalvanism, Intraoral
Microbial Community Analysis
+1 more

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Placebo Group
Group I: : Oral probiotic lozenges + placebo toothpaste (toothpaste without ADP-1)Experimental Treatment2 Interventions
1 active oral probiotic with placebo toothpaste
Group II: Oral probiotic lozenges + toothpaste with ADP-1Active Control1 Intervention
Oral probiotic and ADP1 toothpaste
Group III: Placebo lozenges (lozenges without oral probiotics) + placebo toothpaste (toothpaste without ADP-1)Placebo Group1 Intervention
Placebo without oral probiotics or ADP1 toothpaste
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Placebo
1995
Completed Phase 3
~2670
Oral probiotic
2021
N/A
~110

Find a Location

Who is running the clinical trial?

USANA Health SciencesLead Sponsor
11 Previous Clinical Trials
659 Total Patients Enrolled
Roseman University of Health SciencesOTHER
3 Previous Clinical Trials
291 Total Patients Enrolled
~25 spots leftby Dec 2025