Radiotherapy for Osteoarthritis

Recruiting in Palo Alto (17 mi)

Overseen by Stephen P. Merry, M.D.

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Mayo Clinic

No Placebo Group

Trial Summary

What is the purpose of this trial?

The primary aim of this study is to investigate whether low-dose radiotherapy is an effective treatment to reduce the pain of knee osteoarthritis. A secondary aim is to determine whether patients experience any more measurable side effects than those receiving sham treatments.

Eligibility Criteria

This trial is for individuals with knee osteoarthritis who are experiencing pain. Specific eligibility criteria aren't provided, but typically participants should be adults meeting diagnostic criteria for the condition and able to comply with study requirements.

Inclusion Criteria

I don't have knee pain in specific tendon areas.

My knees are stiff in the morning for less than 30 minutes.

My knee x-rays show moderate arthritis.

Exclusion Criteria

Kellgren-Lawrence grade 1 or 4

My current knee pain was caused by an injury within the last year.

History of psychosis, personality disorder, uncontrolled affective disorder

Participant Groups

The trial is testing if low-dose radiotherapy can reduce knee pain from osteoarthritis compared to a sham (fake) treatment. Participants will be randomly assigned to receive either the real or sham therapy to assess effectiveness and side effects.

Group I: Low dose radiotherapy Active Control 1 Intervention

Low dose radiation therapy for knee osteoarthritis

Group II: Placebo Placebo Group 1 Intervention

No radiation therapy

Find a Clinic Near You

Research Locations Nearby Select from list below to view details:

Mayo Clinic Rochester, MN

Who Is Running the Clinical Trial?

Mayo Clinic Lead Sponsor

References