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Dietary Treatment Study of Fat Synthesis and Risk of Cardiovascular Disease

N/A
Waitlist Available
Led By Kathleen Mulligan, PhD
Research Sponsored by University of California, San Francisco
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up after 10-day dietary period
Awards & highlights
No Placebo-Only Group

Summary

This trial will study how different diets affect the amount of fat people's bodies make, the types of fats in their blood, and how much fat is stored in their liver.

Eligible Conditions
  • Obesity

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~after 10-day dietary period
This trial's timeline: 3 weeks for screening, Varies for treatment, and after 10-day dietary period for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Effect of meal composition on fractional de novo lipogenesis (fatty acid synthesis)
Secondary study objectives
Effect of meal frequency on fractional de novo lipogenesis (fatty acid synthesis)
Other study objectives
Lipids and lipoproteins in the blood
Liver fat content

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

6Treatment groups
Experimental Treatment
Group I: High sugar/nibbleExperimental Treatment2 Interventions
Diet high in simple sugar fed as 8 small meals daily
Group II: High sugar/meal feedExperimental Treatment2 Interventions
Diet high in simple sugar fed as two large meals daily
Group III: High sugar/3 meals a dayExperimental Treatment2 Interventions
Diet high in simple sugar fed as 3 meals a day
Group IV: High fat/nibbleExperimental Treatment1 Intervention
Diet high in fat fed as 8 small meals daily
Group V: High fat/meal feedExperimental Treatment2 Interventions
Diet high in fat fed as two large meals daily
Group VI: High fat/ 3 meals a dayExperimental Treatment2 Interventions
Diet high in fat fed as 3 meals a day

Find a Location

Who is running the clinical trial?

University of California, San FranciscoLead Sponsor
2,592 Previous Clinical Trials
14,901,804 Total Patients Enrolled
35 Trials studying Obesity
11,445 Patients Enrolled for Obesity
Touro University, CaliforniaOTHER
7 Previous Clinical Trials
1,014 Total Patients Enrolled
1 Trials studying Obesity
36 Patients Enrolled for Obesity
Kathleen Mulligan, PhDPrincipal InvestigatorUniversity of California, San Francisco
2 Previous Clinical Trials
49 Total Patients Enrolled
Jean-Marc Schwarz, PhDPrincipal InvestigatorTouro University, California
3 Previous Clinical Trials
137 Total Patients Enrolled
~4 spots leftby Dec 2025