Gene Mutation Identification for Pancreatic Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to collect samples such as blood, saliva, urine, or stool from children to identify genetic mutations that may increase the risk of pancreatic cancer. The focus is on children who have experienced acute recurrent pancreatitis (sudden inflammation of the pancreas) or chronic pancreatitis (long-term inflammation of the pancreas). Participants must have had conditions like repeated episodes of acute pancreatitis or irreversible changes in their pancreas that persist over time. Children involved will also complete questionnaires and quality-of-life assessments annually for four years. This research seeks to find genetic markers that can help identify those at risk of developing pancreatic cancer. As an unphased trial, this study offers participants the opportunity to contribute to groundbreaking research that could lead to early detection and prevention strategies for pancreatic cancer in children.
Do I need to stop my current medications for this trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinator or your doctor.
Why are researchers excited about this trial?
Researchers are excited about this trial because it aims to uncover specific gene mutations linked to high-risk pancreatic cancer in children. Unlike traditional treatment approaches that focus on managing symptoms or targeting the cancer directly, this study focuses on collecting biospecimens like blood, saliva, urine, and stool to identify genetic markers. By pinpointing these mutations, the study could pave the way for more personalized and effective treatments in the future. This approach represents a shift towards precision medicine, where understanding the genetic underpinnings of the disease could lead to earlier detection and tailored interventions, potentially improving outcomes for young patients.
Who Is on the Research Team?
Ying Yuan, PHD
Principal Investigator
M.D. Anderson Cancer Center
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline
Collection of blood, saliva, urine, or stool samples and completion of quality-of-life assessment and questionnaires
Follow-up
Participants complete quality-of-life assessment and questionnaires every 12 months for 4 years, with additional biospecimen collection if needed
Long-term follow-up
Participants are followed up every 12 months after completion of the study
What Are the Treatments Tested in This Trial?
Interventions
- Biospecimen Collection
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
Patients complete QoL assessment and complete questionnaires for over 2 hours every 12 months for 4 years. Patients also undergo collection of blood and/or saliva (if blood samples are not available), urine, or stool at baseline.
Find a Clinic Near You
Who Is Running the Clinical Trial?
M.D. Anderson Cancer Center
Lead Sponsor
National Cancer Institute (NCI)
Collaborator
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.