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Investigations of Amygdala Function Using Neurophysiological Recording and Stimulation

N/A
Waitlist Available
Led By Mahendra Bhati, MD
Research Sponsored by Stanford University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 days
Awards & highlights
No Placebo-Only Group

Summary

This trial uses a special device to study how stimulating a part of the brain called the amygdala affects fear and memory. It involves patients with epilepsy who already have this device implanted. The device can both record brain activity and send electrical signals to help researchers understand these effects. The device is used to treat epilepsy by monitoring brain activity and sending signals to reduce seizures.

Eligible Conditions
  • Panic Attacks
  • Botox
  • Panic Disorder
  • Post-Traumatic Stress Disorder

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 days for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
ECoG (ElectroCorticoGraphy) amplitude changes
Electrocorticogram
EEG(electroencephalography) amplitude changes
+1 more
Secondary study objectives
Electrophysiological changes in EDA
Electrophysiological changes in EMG

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: Neurophysiological recording and stimulation of amygdalaExperimental Treatment2 Interventions
Recording and stimulation of amygdala using Neuropace RNS devices at certain points through out the behavioral tasks.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Amygdala recording and stimulation using Neuropace RNS
2019
N/A
~30
Behavioral tasks
2009
N/A
~1300

Find a Location

Who is running the clinical trial?

National Institute of Mental Health (NIMH)NIH
2,928 Previous Clinical Trials
2,744,996 Total Patients Enrolled
Stanford UniversityLead Sponsor
2,484 Previous Clinical Trials
17,516,098 Total Patients Enrolled
Mahendra Bhati, MDPrincipal InvestigatorStanford University
1 Previous Clinical Trials
795 Total Patients Enrolled
~3 spots leftby Dec 2025
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