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Dental Hygiene and Peri-Implant Tissues Homeostasis Ancillary Study

N/A
Waitlist Available
Led By Georgios Kotsakis, DDS, MS
Research Sponsored by University of Washington
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline
Awards & highlights
No Placebo-Only Group

Summary

This trial is investigating tiny metal pieces from dental implants and their role in causing inflammation and bone loss. It focuses on people with dental implants, especially those with peri-implantitis. The goal is to understand why these metal pieces are released and how they worsen the inflammation.

Eligible Conditions
  • Peri-Implantitis

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 weeks +/- 4 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 weeks +/- 4 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Titanium Dissolution
Secondary study objectives
Expression of pro-inflammatory cytokines in response to titanium

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Implant-specific treatmentExperimental Treatment2 Interventions
Implant brush
Group II: Tooth-borne treatmentActive Control2 Interventions
Titanium curettes
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Peri-implantitis debridement
2017
N/A
~40

Find a Location

Who is running the clinical trial?

University of WashingtonLead Sponsor
1,824 Previous Clinical Trials
1,913,321 Total Patients Enrolled
1 Trials studying Peri-Implantitis
34 Patients Enrolled for Peri-Implantitis
Royalty Research Fund - University of WashingtonOTHER
1 Previous Clinical Trials
148 Total Patients Enrolled
Georgios Kotsakis, DDS, MSPrincipal InvestigatorUTHealth San Antonio
1 Previous Clinical Trials
34 Total Patients Enrolled
1 Trials studying Peri-Implantitis
34 Patients Enrolled for Peri-Implantitis
~4 spots leftby Dec 2025
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