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Cannabis Effects on Sleep, Circadian Rhythms, and Light Sensitivity in Young Adults (CASCILS Trial)

N/A
Waitlist Available
Led By Brant P Hasler, PhD
Research Sponsored by University of Pittsburgh
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
* Age 18-25 years
* Physically and psychiatrically healthy
Timeline
Screening 3 weeks
Treatment Varies
Follow Up discontinuation, 4 weeks
Awards & highlights
No Placebo-Only Group

Summary

The goal of this study is to learn how cannabis use and discontinuation affect sleep, circadian rhythms, and sensitivity to light. The main questions it aims to answer are: 1. Does cannabis use and discontinuation impact sleep drive? 2. Does cannabis use and discontinuation impact light sensitivity and circadian phase?

Eligible Conditions
  • Cannabis Use
  • Sleep
  • Circadian Rhythm

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~discontinuation, 4 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and discontinuation, 4 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Circadian Photosensitivity
Homeostatic Sleep Drive
Retinal Responsivity
Secondary study objectives
Circadian phase

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Cannabis-UsingExperimental Treatment1 Intervention
The cannabis-using arm will consist of 60 young people reporting regular cannabis use. They will participate in a 1-week baseline protocol followed by a 4-week cannabis discontinuation protocol (intervention).
Group II: ControlActive Control1 Intervention
The control arm will consist of 30 young people without current cannabis use. They will participate in a 1-week baseline protocol. No intervention will be administered.

Find a Location

Who is running the clinical trial?

University of PittsburghLead Sponsor
1,792 Previous Clinical Trials
16,359,796 Total Patients Enrolled
16 Trials studying Sleep
2,506 Patients Enrolled for Sleep
National Institute on Drug Abuse (NIDA)NIH
2,605 Previous Clinical Trials
3,329,738 Total Patients Enrolled
1 Trials studying Sleep
96 Patients Enrolled for Sleep
Brant P Hasler, PhDPrincipal InvestigatorUniversity of Pittsburgh
1 Previous Clinical Trials
148 Total Patients Enrolled
~120 spots leftby Jan 2029