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Water Seal vs. Suction for Collapsed Lung (SEAL IT Trial)

N/A

Recruiting

Research Sponsored by Vanderbilt University Medical Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Admitted to the trauma surgery service

Pneumothorax requiring a chest tube

Must not have

Less than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up through study completion, an average of 1 year

Awards & highlights

No Placebo-Only Group

Summary

This trial aims to see if starting chest tubes with water seal or suction first leads to shorter chest tube use in patients with traumatic pneumothoraces. Patients will have their chest tubes set to either water

Who is the study for?

This trial is for adults with a collapsed lung due to trauma who need a chest tube and are under the care of the trauma surgery service. It's not for those under 18, pregnant women, prisoners, or patients with over 300cc of blood in the chest or a chest tube placed before CT scans.

What is being tested?

The SUC IT trial is testing whether starting with a water seal rather than suction on chest tubes can reduce how long patients need them after traumatic pneumothorax without increasing complications. The method used alternates monthly.

What are the potential side effects?

Potential side effects may include discomfort at the tube site, infection risk, breathing difficulties if complications arise from treatment methods (water seal vs. suction), but specific side effects will depend on individual patient responses.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am under the care of the trauma surgery team.

Select...

I have had a collapsed lung treated with a chest tube.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

Select...

I am under 18 years old.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ through study completion, an average of 1 year

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~through study completion, an average of 1 year

This trial's timeline: 3 weeks for screening, Varies for treatment, and through study completion, an average of 1 year for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Chest tube duration

Secondary study objectives

30-day mortality

30-day readmission

Acute respiratory failure requiring intubation

+15 more

Other study objectives

Chest tube related costs

Discharge disposition

Length of ICU stay

+5 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups

Experimental Treatment

Group I: Initial Water SealExperimental Treatment1 Intervention

After chest tube placement, the chest tube will be placed to 20cm H2O of suction for 1 minute to evacuate all pneumothorax. After this, the chest tube will be placed to water seal, defined as the water seal chamber on the chest tube drainage system being filled up to the 2cm line and not on suction. All other management decisions related to the chest tube will be left to the providers.

Group II: Initial SuctionExperimental Treatment1 Intervention

After chest tube placement, the suction group will have their chest tube placed to 20cm H2O of suction delivered by the chest tube drainage suction. All other management decisions related to the chest tube will be left to the providers.

0 / 3Eligibility criteria met