Extracellular Vesicle Analysis for Prostate Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial examines how prostate cancer treatment affects certain particles in the blood and urine. These particles, known as extracellular vesicles, might indicate how well a patient responds to prostate cancer surgery. The trial collects samples from both prostate cancer patients and female volunteers for comparison. Men with high-risk prostate cancer, such as those with a PSA level over 20 or a Gleason score of 8 or higher, might be suitable candidates. As a Phase 2 trial, this research measures the treatment's effectiveness in an initial, smaller group, offering participants a chance to contribute to important advancements in prostate cancer treatment.
Do I need to stop my current medications for this trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
Why are researchers excited about this trial?
Researchers are excited about this trial because it aims to understand the baseline levels of prostate cancer-derived extracellular vesicles after local treatment. Unlike traditional treatments that focus on directly targeting cancer cells, this study looks at tiny particles released by prostate cancer cells to see how they change after treatment. By analyzing blood and urine samples, scientists hope to uncover new insights into how prostate cancer behaves and potentially develop new markers for monitoring the disease. This could lead to more personalized and effective treatment strategies in the future.
Who Is on the Research Team?
Eugene D. Kwon, M.D.
Principal Investigator
Mayo Clinic in Rochester
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Pre-surgery
Blood and urine samples are collected from prostate cancer patients before radical prostatectomy
Post-surgery
Blood and urine samples are collected once post-surgery, 6 weeks to 6 months after surgery
Follow-up
Annual blood collection for ongoing monitoring of prostate cancer-derived EV levels
What Are the Treatments Tested in This Trial?
Interventions
- Non-Interventional Study
How Is the Trial Designed?
3
Treatment groups
Experimental Treatment
Female urology clinic patients and female volunteers undergo blood and urine sample collection on study.
Prostate cancer patients undergo blood and urine sample collection throughout the study. Patients' medical records are also reviewed.
Prostate cancer patients undergo blood and urine sample collection on study. Patients' medical records are also reviewed.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Mayo Clinic
Lead Sponsor
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