Effect of Radiotherapy Variables on Circulating Effectors of Immune Response and Local Microbiome

Recruiting in Palo Alto (17 mi)

Overseen by Silvia Formenti, M.D.

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Weill Medical College of Cornell University

No Placebo Group

Trial Summary

What is the purpose of this trial?

Exposure to radiation can impact immune cells that are present in the blood, such as lymphocytes. It is hypothesized that larger radiation fields and/or longer courses of radiation, result in greater decrease in immune cells. To test this hypothesis, investigators will take blood samples from subjects undergoing two different standard of care radiation regimens for prostate cancer, and subjects undergoing two different standard of care regimens for breast cancer.

Eligibility Criteria

Inclusion Criteria

Cohort 1a and b: Prostate cancer subjects undergoing 9 week radiation

Biopsy-proven diagnosis of prostate adenocarcinoma

Age ≥ 18

Treatment Details

Interventions

• Standard of Care Radiation Regimens for Prostate Cancer (Radiation)
• Standard of Care Regimens for Breast Cancer (Radiation)

Find a Clinic Near You

Research Locations Nearby Select from list below to view details:

Weill Cornell Medical College New York, NY

Who Is Running the Clinical Trial?

Weill Medical College of Cornell University Lead Sponsor

Varian Medical Systems Industry Sponsor

References