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MRI Software and Techniques
RSI-MRI for Early Detection of Prostate Cancer (IMAGINED Trial)
San Antonio, TX
N/A
Recruiting
Led By Michael A Liss, MD, PhD
Research Sponsored by The University of Texas Health Science Center at San Antonio
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline to approximately 9 months
Awards & highlights
No Placebo-Only Group
Summary
This trial will explore if MRI tech can help spot early prostate cancer, improving accuracy of biopsies.
Who is the study for?
This trial is for men selected to undergo an MRI-guided prostate needle biopsy. Participants must be able to understand and agree to the study's procedures by providing informed consent.
What is being tested?
The IMAGINED Trial is testing if advanced MRI software, called Restricted Spectrum Imaging-MRI (RSI-MRI), can improve early detection of prostate cancer during a biopsy procedure.
What are the potential side effects?
Since this trial involves imaging techniques rather than drugs, side effects are minimal but may include discomfort from lying still during the MRI or from the biopsy procedure itself.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ baseline to approximately 9 months
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline to approximately 9 months
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
RSM mapping value
Awards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Trial Design
3Treatment groups
Experimental Treatment
Group I: MRI imaging using Siemens MRIExperimental Treatment1 Intervention
Participants enrolled will undergo routine Magnetic Resonance Imaging (MRI) to obtain Restricted Spectrum Mapping (RSM). These sequences are acquired at the same time as standard multi-parametric MRI sequences. Second post-processing software then transfers the acquired RSI images from DICOM format and applies a color-coded image that is then overlayed onto the anatomic T2 image.
Group II: MRI imaging using Phillips MRIExperimental Treatment1 Intervention
Participants enrolled will undergo routine MRI to obtain RSM. These sequences are acquired at the same time as standard multi-parametric MRI sequences. Second post-processing software then transfers the acquired RSI images from DICOM format and applies a color-coded image that is then overlayed onto the anatomic T2 image.
Group III: MRI imaging using General Electric (GE) MRIExperimental Treatment1 Intervention
Participants enrolled will undergo routine MRI to obtain RSM. These sequences are acquired at the same time as standard multi-parametric MRI sequences. Second post-processing software then transfers the acquired RSI images from DICOM format and applies a color-coded image that is then overlayed onto the anatomic T2 image.
Find a Location
Closest Location:University Health System· San Antonio, TX
Who is running the clinical trial?
National Cancer Institute (NCI)NIH
13,958 Previous Clinical Trials
41,112,355 Total Patients Enrolled
515 Trials studying Prostate Cancer
332,735 Patients Enrolled for Prostate Cancer
The University of Texas Health Science Center at San AntonioLead Sponsor
477 Previous Clinical Trials
92,745 Total Patients Enrolled
12 Trials studying Prostate Cancer
3,000 Patients Enrolled for Prostate Cancer
Michael A Liss, MD, PhDPrincipal InvestigatorUniversity of Texas Health Science Center San Antonio
1 Previous Clinical Trials
50 Total Patients Enrolled
1 Trials studying Prostate Cancer
50 Patients Enrolled for Prostate Cancer
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I cannot safely stop my blood thinner medication for a prostate biopsy.My prostate cancer has spread to other parts of my body.I am unable to understand and agree to the study's details on my own.I have had treatment for prostate cancer before.I was previously diagnosed with prostate cancer that was more serious than the lowest grade.I have had both of my hips replaced.I am chosen for a specific prostate biopsy using MRI guidance.
Research Study Groups:
This trial has the following groups:- Group 1: MRI imaging using General Electric (GE) MRI
- Group 2: MRI imaging using Siemens MRI
- Group 3: MRI imaging using Phillips MRI
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.