Respiratory Support in Severe Chronic Obstructive Pulmonary Disease Exacerbation
Recruiting in Palo Alto (17 mi)
Overseen ByQingyuan Zhan, M.D.
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: China-Japan Friendship Hospital
No Placebo Group
Trial Summary
What is the purpose of this trial?Preliminary studies have shown that NPPV can avoid tracheal intubation in 40% to 60% patients who have severe exacerbation of COPD. Recently, large-scale comparative effectiveness research (CER) also found that compared with invasive ventilation, NPPV can reduce mortality rates. But there's no high-quality clinical studies which can confirm this. Therefore, investigators believe that NPPV can avoid intubation in patients with severe exacerbation of COPD in ICU with perfect monitoring conditions and reasonable human resource allocation, in order to reduce IMV-related complications and improve patients' outcomes.
Eligibility Criteria
Inclusion Criteria
AECOPD;
Participant Groups
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Who Is Running the Clinical Trial?
China-Japan Friendship HospitalLead Sponsor