MR-Guided Cryoablation for Recurrent Prostate Cancer

Recruiting in Palo Alto (17 mi)

Overseen ByDavid Woodrum, MD, PhD

Age: 18+

Sex: Male

Travel: May be covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Mayo Clinic

No Placebo Group

Trial Summary

What is the purpose of this trial?The purpose of this research is to see if MR-guided cryoablation can effectively treat prostate tumor recurrences.

Eligibility Criteria

This trial is for adults with prostate cancer that has come back and shows up in the area where the prostate used to be. The tumor must be smaller than 5 cm, not involve certain areas like the rectal wall, and patients should be healthy enough for MRI scans. It's aimed at those who can't have or don't want surgery right now, and whose cancer hasn't responded to or isn't suitable for radiation therapy.

Inclusion Criteria

My prostate cancer has returned and is confirmed by a biopsy.

My tumor is smaller than 5 cm across.

My tumor does not involve the rectal wall or the external urethral sphincter.

Surgery is not a good option for my condition right now.

Participant Groups

The study is testing MR-guided cryoablation—a way of freezing tumors using magnetic resonance imaging to guide the process—to see if it's effective in treating prostate cancer recurrences located where the prostate was previously removed.

1Treatment groups

Experimental Treatment

Group I: MR-guided cryoablation (freezing of tissue and/or tumors)Experimental Treatment1 Intervention

Patients undergo cryoablation using the Galil MR-compatible cryoablation system and MRI while on study.