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Procedure

MR-Guided Cryoablation for Recurrent Prostate Cancer

N/A
Waitlist Available
Led By David Woodrum, MD, PhD
Research Sponsored by Mayo Clinic
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Patients with biopsy proven soft tissue tumor recurrences of prostate fossa
Tumor size is less than 5 cm at its largest diameter
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights
No Placebo-Only Group

Summary

This trial will test whether MR-guided cryoablation can effectively shrink prostate tumors that have come back.

Who is the study for?
This trial is for adults with prostate cancer that has come back and shows up in the area where the prostate used to be. The tumor must be smaller than 5 cm, not involve certain areas like the rectal wall, and patients should be healthy enough for MRI scans. It's aimed at those who can't have or don't want surgery right now, and whose cancer hasn't responded to or isn't suitable for radiation therapy.
What is being tested?
The study is testing MR-guided cryoablation—a way of freezing tumors using magnetic resonance imaging to guide the process—to see if it's effective in treating prostate cancer recurrences located where the prostate was previously removed.
What are the potential side effects?
While specific side effects are not listed here, cryoablation procedures may generally include risks such as pain at the treatment site, swelling, bruising, infection risk, tissue damage around treated areas including nerves or blood vessels.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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My prostate cancer has returned and is confirmed by a biopsy.
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My tumor is smaller than 5 cm across.
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My tumor does not involve the rectal wall or the external urethral sphincter.
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Surgery is not a good option for my condition right now.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: MR-guided cryoablation (freezing of tissue and/or tumors)Experimental Treatment1 Intervention
Patients undergo cryoablation using the Galil MR-compatible cryoablation system and MRI while on study.

Find a Location

Who is running the clinical trial?

Mayo ClinicLead Sponsor
3,337 Previous Clinical Trials
3,061,067 Total Patients Enrolled
27 Trials studying Prostate Cancer
6,973 Patients Enrolled for Prostate Cancer
David Woodrum, MD, PhDPrincipal InvestigatorMayo Clinic
4 Previous Clinical Trials
32 Total Patients Enrolled
1 Trials studying Prostate Cancer
10 Patients Enrolled for Prostate Cancer

Media Library

MR-guided cryoablation (Procedure) Clinical Trial Eligibility Overview. Trial Name: NCT01727284 — N/A
Prostate Cancer Research Study Groups: MR-guided cryoablation (freezing of tissue and/or tumors)
Prostate Cancer Clinical Trial 2023: MR-guided cryoablation Highlights & Side Effects. Trial Name: NCT01727284 — N/A
MR-guided cryoablation (Procedure) 2023 Treatment Timeline for Medical Study. Trial Name: NCT01727284 — N/A
~15 spots leftby Nov 2026
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