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Survivors of early-onset colorectal cancer, with recurrent disease (Training Cohort) for Colorectal Cancer (ENCORE Trial)

N/A
Waitlist Available
Led By Ajay Goel, PhD
Research Sponsored by City of Hope Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 120 months
Awards & highlights
No Placebo-Only Group

Summary

This trial aims to help young adults who survived early-onset colorectal cancer by using a test that looks at tiny molecules in their tumors. The test uses computer algorithms to predict if and when the cancer might come back, helping doctors make better decisions about monitoring and treatment.

Eligible Conditions
  • Colorectal Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 120 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 120 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Recurrence Free Survival
Secondary study objectives
Overall Survival

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

4Treatment groups
Experimental Treatment
Group I: Survivors of early-onset colorectal cancer, with recurrent disease (Validation Cohort)Experimental Treatment1 Intervention
Survivors of early-onset colorectal cancer who developed recurrent CRC within 60 months from primary tumor treatment, in the second, independent, validation cohort
Group II: Survivors of early-onset colorectal cancer, with recurrent disease (Training Cohort)Experimental Treatment1 Intervention
Survivors of early-onset colorectal cancer who developed recurrent CRC within 60 months from primary tumor treatment, in the first cohort
Group III: Survivors of early-onset colorectal cancer, with no recurrent disease (Validation Cohort)Experimental Treatment1 Intervention
Survivors of early-onset colorectal cancer who did not develop recurrent CRC within 60 months from primary tumor treatment, in the second, independent, validation cohort
Group IV: Survivors of early-onset colorectal cancer, with no recurrent disease (Training Cohort)Experimental Treatment1 Intervention
Survivors of early-onset colorectal cancer who did not develop recurrent CRC within 60 months from primary tumor treatment, in the first cohort

Find a Location

Who is running the clinical trial?

City of Hope Medical CenterLead Sponsor
598 Previous Clinical Trials
1,923,199 Total Patients Enrolled
IRCCS San Raffaele Hospital, Milan, ItalyUNKNOWN
2 Previous Clinical Trials
10,683 Total Patients Enrolled
Institute of Biomedical Research of Salamanca, Salamanca, SpainUNKNOWN
~71 spots leftby Oct 2025
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