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Low Salicylate Diet in Aspirin Exacerbated Respiratory Disease

N/A
Waitlist Available
Research Sponsored by Hamilton Health Sciences Corporation
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
* Clinical diagnosis of AERD
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 weeks and 12 weeks
Awards & highlights
No Placebo-Only Group

Summary

This trial is testing if a diet low in salicylates can improve the quality of life for people with Aspirin Exacerbated Respiratory Disease (AERD). These patients often have severe reactions to aspirin and struggle with asthma, nasal polyps, and chronic sinusitis. By eating foods with fewer salicylates, the study aims to see if their symptoms can be reduced without the risks associated with daily aspirin use. Initial findings indicated that a low salicylate diet improves nasal symptoms and nasal endoscopy findings in individuals with AERD.

Eligible Conditions
  • Respiratory Disease
  • Samter's Triad

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 weeks and 12 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 weeks and 12 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Change in SNOT-22 scores from Baseline
Secondary study objectives
Change in Lund-Kennedy Endoscopic Score from Baseline

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: DietExperimental Treatment1 Intervention
Group II: ControlActive Control1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Low salicylate diet
2013
N/A
~10

Find a Location

Who is running the clinical trial?

Hamilton Health Sciences CorporationLead Sponsor
377 Previous Clinical Trials
339,849 Total Patients Enrolled
~6 spots leftby Dec 2025
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