Remote Exercise Program for Rheumatoid Arthritis

(TRAINERa Trial)

Overseen by Brian J Andonian, MD, MHSc

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Duke University

No Placebo Group

Trial Summary

What is the purpose of this trial?

The primary objective of this study is to assess the feasibility of an intensive, remotely-delivered, combined aerobic and resistance training exercise program for patients with Rheumatoid Arthritis (RA) and to collect data to support power calculations for a larger research study.

Research Team

Brian J Andonian, MD, MHSc

Principal Investigator

Duke University

Eligibility Criteria

This trial is for individuals with Rheumatoid Arthritis who can participate in an intensive exercise program delivered remotely. Specific eligibility criteria are not provided, but typically participants would need to be stable enough to engage in physical activity and have internet access for remote participation.

Inclusion Criteria

History of fulfilling 2010 ACR/EULAR Classification Criteria for RA

I was diagnosed with RA less than 6 months ago and haven't started biologic DMARD therapy.

I have positive tests or signs of rheumatoid arthritis on X-rays.

Exclusion Criteria

Pregnant or intending to become pregnant during the intervention period

Lack of internet access

I do not have conditions like Paget's disease or hemochromatosis affecting my joints or muscles.

Treatment Details

Interventions

• TRAINERa intensive exercise training (Behavioral Intervention)

Trial Overview The study is testing a new intensive exercise training program called TRAINERa, which combines aerobic and resistance exercises. It's designed specifically for people with Rheumatoid Arthritis and is delivered through remote means to assess its feasibility.

Participant Groups

Group I: TRAINERa intensive exercise training Experimental Treatment 1 Intervention

Participants with early and active rheumatoid arthritis (RA) will complete a 12-week RA-tailored remotely supervised and delivered moderate to vigorous intensity aerobic training combined with resistance training exercise program.

Who Is Running the Clinical Trial?

Duke University

Lead Sponsor

Trials

2,495

Recruited

5,912,000+

Mary E. Klotman

Duke University

Chief Executive Officer since 2017

MD from Duke University School of Medicine

Michelle McMurry-Heath

Duke University

Chief Medical Officer since 2020

MD from Duke University School of Medicine