Detection and Treatment of Sarcopenia and Myosteatosis in Older African Americans
(ARMS-II Trial)
Recruiting in Palo Alto (17 mi)
+2 other locations
Overseen byMichael Harris-Love, DSc MPT BS
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: VA Office of Research and Development
No Placebo Group
Trial Summary
What is the purpose of this trial?The objectives of this study are to: 1) validate a rapid, portable, cost-effective method for screening myosteatosis and sarcopenia using diagnostic ultrasound, and 2) investigate a novel approach to progressive resistance exercise involving eccentric muscle actions that will counter the local effects of myosteatosis and sarcopenia in African Americans.
Eligibility Criteria
Inclusion Criteria
An African American adult.
Between 18 and 30 years of age, or between 65 and 85 years of age.
Able to independently walk at home and in your community (use of an assistive device like a cane or a walker is acceptable).
Participant Groups
2Treatment groups
Experimental Treatment
Active Control
Group I: Eccentric ExerciseExperimental Treatment1 Intervention
Supervised strengthening exercise using eccentric muscle actions.
Group II: Concentric ExerciseActive Control1 Intervention
Supervised strengthening exercise using concentric muscle actions.
Find a Clinic Near You
Research Locations NearbySelect from list below to view details:
Rocky Mountain Regional VA Medical Center, Aurora, COAurora, CO
University of Colorado Anschutz Medical CampusAurora, CO
Howard UniversityWashington, United States
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Who Is Running the Clinical Trial?
VA Office of Research and DevelopmentLead Sponsor