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Behavioral Intervention

Eccentric Exercise for Sarcopenia (ARMS-II Trial)

N/A
Waitlist Available
Led By Michael Harris-Love, DSc MPT BS
Research Sponsored by VA Office of Research and Development
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up at study baseline for all subjects, and at week 6 and 12 of the intervention period for subjects randomly assigned to an exercise group
Awards & highlights
No Placebo-Only Group

Summary

This trial is testing a new way to use ultrasound to screen for muscle conditions and a new type of exercise to help people with those conditions.

Eligible Conditions
  • Sarcopenia

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~at study baseline for all subjects
This trial's timeline: 3 weeks for screening, Varies for treatment, and at study baseline for all subjects for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Change from Baseline in Sonographic Lean Body Mass at 3 months
Secondary study objectives
Change from Baseline in dual-energy X-ray absorptiometry (DXA) scanning at 3 months
Adipose tissue
Change from Baseline in metabolic status at 3 months
+1 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Eccentric ExerciseExperimental Treatment1 Intervention
Supervised strengthening exercise using eccentric muscle actions.
Group II: Concentric ExerciseActive Control1 Intervention
Supervised strengthening exercise using concentric muscle actions.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Eccentric Exercise
2009
N/A
~180

Find a Location

Who is running the clinical trial?

VA Office of Research and DevelopmentLead Sponsor
1,664 Previous Clinical Trials
3,765,668 Total Patients Enrolled
3 Trials studying Sarcopenia
263 Patients Enrolled for Sarcopenia
Michael Harris-Love, DSc MPT BSPrincipal InvestigatorRocky Mountain Regional VA Medical Center, Aurora, CO
2 Previous Clinical Trials
250 Total Patients Enrolled
1 Trials studying Sarcopenia
~13 spots leftby Nov 2025
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