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Protein-rich Diet and Exercise for Aging Muscles

N/A

Waitlist Available

Led By Chad Carroll, PhD

Research Sponsored by Purdue University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Women with HbA1c less than 6.5% (non-diabetic)

Women 60-80 years old.

Must not have

Individuals with any orthopedic condition that would prevent them from properly performing exercise.

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 6 and 12 weeks

Awards & highlights

No Placebo-Only Group

Summary

This trial will compare the effects of consuming a healthy, protein-rich diet emphasizing lean beef, compared to a healthy, normal-protein, lower beef diet (control 1), and a healthy protein-rich, lower beef diet emphasizing non-beef/red meat protein (control 2) on resistance training-induced changes in muscle and tendon tissue size, strength, and quality in older women.

Who is the study for?

This trial is for women aged 60-80 with a BMI under 40 and non-diabetic HbA1c levels. Participants must be able to do resistance training exercises but can't join if they regularly take painkillers, use tobacco, have claustrophobia or metal implants that prevent MRI scans, or any orthopedic issues affecting exercise.

What is being tested?

The study tests the effects of a protein-rich diet with lean beef on muscle and tendon strength during resistance training in older women. It compares this diet to two controls: one with normal-protein and lower beef intake, and another emphasizing non-beef proteins.

What are the potential side effects?

While not explicitly stated, potential side effects may include typical risks associated with dietary changes such as digestive discomfort. Resistance training could lead to muscle soreness or injury if not performed correctly.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

My HbA1c level is below 6.5%, indicating I am not diabetic.

Select...

I am a woman aged between 60 and 80.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

Select...

I do not have any bone or joint problems that would stop me from exercising.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 6 and 12 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~6 and 12 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 and 12 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Patellar Tendon Size

Skeletal Muscle Mass

Skeletal Muscle Strength

+1 more

Secondary study objectives

Blood glucose

Cholesterol

HbA1c

+1 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

3Treatment groups

Experimental Treatment

Group I: normal protein dietExperimental Treatment1 Intervention

The normal protein diet (Control) will contain the RDA for protein of (0.8 g/kg/d), with the protein provided from a variety of animal and plant-based sources, including lean beef (one 3-oz portion per week), chicken, eggs, dairy, beans, grains, nuts, seeds.

Group II: a protein-rich diet non-red meatExperimental Treatment1 Intervention

High-protein group from a variety of animal and plant-based sources (excluding additional red meats).

Group III: a beef protein-rich dietExperimental Treatment1 Intervention

High protein diet predominantly provided from lean beef (one 3-oz portion per day; total beef intake 24 oz/week). The energy content of the additional protein foods will be isocalorically offset by substitution for low-protein foods.

0 / 3Eligibility criteria met