Digital App for Stem Cell Transplant Survivors
(SHIFT Trial)

Recruiting in Palo Alto (17 mi)

+2 other locations

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Massachusetts General Hospital

No Placebo Group

Trial Summary

What is the purpose of this trial?This research study is evaluating the efficacy of a novel self-administered digital application for improving sexual health outcomes, quality of life, and psychological distress in hematopoietic stem cell transplant survivors.

Eligibility Criteria

This trial is for individuals who have undergone a hematopoietic stem cell transplant and are experiencing sexual dysfunction or complications from the procedure. Participants should be interested in using a digital application to improve their sexual health, quality of life, and psychological well-being.

Inclusion Criteria

I had a stem cell transplant more than three months ago.

Screen positive for sexual health concerns causing distress based on the National Comprehensive Network (NCCN) survivorship guidelines screening questions

Exclusion Criteria

I do not have any severe mental health issues that would prevent me from understanding and consenting to the study.

I understand either English or Spanish.

Participant Groups

The study is testing a new self-help digital app called SHIFT designed to help stem cell transplant survivors with their sexual health. It compares outcomes between those using SHIFT and those receiving enhanced usual care without the app.

2Treatment groups

Experimental Treatment

Active Control

Group I: SHIFT Intervention GroupExperimental Treatment1 Intervention

SHIFT is a self-administered, multi-component digital application for HCT survivors, incorporating several features to promote engagement and health behavior change, and includes gamification strategies, videos of HCT survivors, intimacy exercises, and optional content.

Group II: Enhanced Usual Care GroupActive Control1 Intervention

Patients assigned to enhanced usual care group will not receive access to the SHIFT application. They will meet with their HCT clinician and maybe referred to specialist care at the patients' request or at the discretion of the HCT clinician.