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Oropharyngeal Exercises and Post-Stroke Obstructive Sleep Apnea

N/A
Waitlist Available
Led By Mark Boulos, MD MSc FRCPC
Research Sponsored by Sunnybrook Health Sciences Centre
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, 6-10 weeks (post-training), and 10-14 weeks (retention)

Summary

This trial tests whether doing exercises to strengthen the muscles around the throat can improve sleep apnea in people who have had a stroke, as an alternative to using a machine to help them breathe at night.

Eligible Conditions
  • Stroke
  • Sleep Apnea
  • Mini-stroke
  • Apnea Test
  • Apnea
  • Obstructive Sleep Apnea

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, 6-10 weeks (post-training), and 10-14 weeks (retention)
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 6-10 weeks (post-training), and 10-14 weeks (retention) for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Percentage of enrolled participants completing >80% of the study exercises
Secondary study objectives
Cognitive ability (as measured by Montreal Cognitive Assessment)
Daytime sleepiness (as measured by Epworth Sleepiness Scale)
Fatigue
+7 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Oro-pharyngeal exercisesExperimental Treatment1 Intervention
Use of oro-pharyngeal exercises
Group II: Sham controlPlacebo Group1 Intervention
Use of sham exercises.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Oropharyngeal exercises
2019
Completed Phase 3
~70

Find a Location

Who is running the clinical trial?

Sunnybrook Research InstituteOTHER
32 Previous Clinical Trials
215,765 Total Patients Enrolled
5 Trials studying Stroke
257 Patients Enrolled for Stroke
University of TorontoOTHER
725 Previous Clinical Trials
1,115,663 Total Patients Enrolled
23 Trials studying Stroke
4,371 Patients Enrolled for Stroke
Toronto Rehabilitation InstituteOTHER
54 Previous Clinical Trials
5,993 Total Patients Enrolled
14 Trials studying Stroke
3,109 Patients Enrolled for Stroke
Sunnybrook Health Sciences CentreLead Sponsor
681 Previous Clinical Trials
1,565,725 Total Patients Enrolled
24 Trials studying Stroke
6,990 Patients Enrolled for Stroke
Unity Health TorontoOTHER
562 Previous Clinical Trials
453,918 Total Patients Enrolled
10 Trials studying Stroke
4,252 Patients Enrolled for Stroke
Mark Boulos, MD MSc FRCPCPrincipal InvestigatorSunnybrook Health Sciences Centre
Yana Yunusova, MSc PhDPrincipal InvestigatorSunnybrook Health Sciences Centre
~5 spots leftby Jan 2026
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