← Back to Search

rh-BMP2 for Spondylosis

N/A
Waitlist Available
Led By Eric Klineberg, M.D.
Research Sponsored by SeaSpine, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12 months
Awards & highlights

Summary

The objective of this study is to prospectively evaluate the performance of Integra Accell Evo3 Demineralized Bone Matrix as an adjunct for posterolateral spine fusion with a retrospective comparison to a historical patient cohort.

Eligible Conditions
  • Spondylosis
  • Degenerative Changes
  • Stenosis

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Number of Radiographic Assessments That Indicate Posterolateral Fusion at 12 Months Post Surgery

Trial Design

2Treatment groups
Experimental Treatment
Group I: rh-BMP2Experimental Treatment1 Intervention
A retrospective cohort of patients who were age- and sex- matched to the prospective cohort who underwent posterolateral lumbar fusion with use of rh-BMP2
Group II: Demineralized Bone MatrixExperimental Treatment1 Intervention
a prospective cohort of patients undergoing posterolateral lumbar fusion with Evo3 in the posterolateral space
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
rh-BMP2
2011
N/A
~50
Demineralized Bone Matrix
2011
N/A
~50

Find a Location

Who is running the clinical trial?

SeaSpine, Inc.Lead Sponsor
8 Previous Clinical Trials
2,484 Total Patients Enrolled
3 Trials studying Spondylosis
95 Patients Enrolled for Spondylosis
Eric Klineberg, M.D.Principal InvestigatorUniversity of CA - Davis
~3 spots leftby Sep 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top