Observational Study for Stargardt Disease
(POLARIS Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to observe the progression of Stargardt Disease Type 1 (STGD1), a genetic eye condition caused by specific mutations, over time. Researchers are not testing a new treatment; instead, they focus on understanding the disease's natural course. Suitable candidates for this study include individuals diagnosed with STGD1 who have experienced worsening symptoms in the past two years. Participants should also be able to undergo detailed eye imaging without complications. As an unphased trial, this study allows participants to contribute to a deeper understanding of STGD1, potentially aiding future research and treatment strategies.
Why are researchers excited about this trial?
Researchers are excited about this trial because it aims to gather crucial information on the progression of Stargardt Disease Type 1 (STGD1) caused by mutations in the ABCA4 gene. Unlike existing treatments that primarily focus on managing symptoms, this observational study seeks to better understand the disease's natural history and progression. By closely monitoring patients over time, the study could pave the way for future targeted therapies that address the root causes of the disease, potentially leading to more effective treatments.
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Observational
Participants are observed to follow the progression of Stargardt Disease Type 1 (STGD1) and to enhance understanding of disease progression and structural and functional markers.
Follow-up
Participants are monitored for safety and effectiveness after the observational period
What Are the Treatments Tested in This Trial?
Find a Clinic Near You
Who Is Running the Clinical Trial?
Splice Bio
Lead Sponsor