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Procedure

Blood Flow Restriction Exercise for Arterial Stiffness

N/A
Recruiting
Research Sponsored by Salisbury University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 10 minutes after exercise trial.
Awards & highlights

Study Summary

This trial looks at the effects of autoregulated & non-autoregulated blood flow restriction arm curls on arterial stiffness in 20 adults. Tests & exercise will be done to compare physiological changes.

Who is the study for?
This trial is for physically active women aged 18-40 with regular menstrual cycles, who have been weight stable. It's not suitable for those with a history of cardiovascular disease, high blood pressure, extreme obesity (BMI>40), diabetes, recent surgery, sleep apnea, liver or kidney disease, claustrophobia or if pregnant/nursing.Check my eligibility
What is being tested?
The study tests how bicep curls with different levels of blood flow restriction affect arterial stiffness in healthy adults. Participants will try three types of arm exercises: without restriction (control), autoregulated and non-autoregulated BFR using the Delfi Personal Tourniquet Systems.See study design
What are the potential side effects?
While specific side effects are not listed for this exercise-based intervention, participants may experience discomfort from the tourniquet system or muscle fatigue due to the exercise protocol.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~10 minutes after exercise trial.
This trial's timeline: 3 weeks for screening, Varies for treatment, and 10 minutes after exercise trial. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Beta-Stiffness Index
Carotid-femoral pulse wave velocity

Trial Design

3Treatment groups
Active Control
Group I: Autoregulated blood flow restrictionActive Control1 Intervention
Autoregulated BFR expands as the muscle progresses into the stretch-shortening cycle.
Group II: Non-autoregulated blood flow restrictionActive Control1 Intervention
Non-autoregulated BFR does not expand as the muscle progresses into the stretch-shortening cycle.
Group III: No blood flow restrictionActive Control1 Intervention
This group serves as the control group for this study

Find a Location

Who is running the clinical trial?

Salisbury UniversityLead Sponsor
3 Previous Clinical Trials
65 Total Patients Enrolled

Media Library

Autoregulated and Non-autoregulated Blood Flow Restrictive Bicep Curls (Procedure) Clinical Trial Eligibility Overview. Trial Name: NCT05748821 — N/A
Healthy Lifestyle Research Study Groups: Autoregulated blood flow restriction, Non-autoregulated blood flow restriction, No blood flow restriction
Healthy Lifestyle Clinical Trial 2023: Autoregulated and Non-autoregulated Blood Flow Restrictive Bicep Curls Highlights & Side Effects. Trial Name: NCT05748821 — N/A
Autoregulated and Non-autoregulated Blood Flow Restrictive Bicep Curls (Procedure) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05748821 — N/A
~9 spots leftby Jun 2025
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