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Stroke patients with moderate-to-severe pre-stroke disability for Stroke (TESTED Trial)

N/A
Recruiting
Led By J Mocco, MD
Research Sponsored by University of Cincinnati
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 90 (±14) days after treatment initiation
Awards & highlights

Summary

TESTED will compare the risks and benefits of endovascular thrombectomy (EVT) to medical management (no EVT) in ischemic stroke patients who have a blockage in one of the large blood vessels in the brain and have a moderate-to-severe disability prior to their stroke.

Eligible Conditions
  • Stroke
  • Ischemic Stroke

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~90 (±14) days after treatment initiation
This trial's timeline: 3 weeks for screening, Varies for treatment, and 90 (±14) days after treatment initiation for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Secondary outcome measures
Academic Medical Center - Linear Disability Scale (ALDS)
Disability-weighted (or utility-weighted) mRS
EQ-5D-5L
+1 more
Other outcome measures
Barthel Index Scale
Extended Thrombolysis in Cerebral Ischemia scale
Initial residence level or better time during first 90 days post-stroke
+4 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: Stroke patients with moderate-to-severe pre-stroke disabilityExperimental Treatment2 Interventions
Patients with pre-stroke modified Rankin scale score 3 or 4, presenting with a anterior circulation large vessel occlusion stroke within 24 hours of last known well

Find a Location

Who is running the clinical trial?

University of CincinnatiLead Sponsor
433 Previous Clinical Trials
635,343 Total Patients Enrolled
31 Trials studying Stroke
15,164 Patients Enrolled for Stroke
Icahn School of Medicine at Mount SinaiOTHER
886 Previous Clinical Trials
533,983 Total Patients Enrolled
14 Trials studying Stroke
6,258 Patients Enrolled for Stroke
Patient-Centered Outcomes Research InstituteOTHER
568 Previous Clinical Trials
27,248,349 Total Patients Enrolled
6 Trials studying Stroke
170,061 Patients Enrolled for Stroke
~707 spots leftby Jan 2028
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