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Robot-assisted Therapy

Robot + TTT Exercise for Stroke (SRT5 Trial)

N/A
Waitlist Available
Led By George Wittenberg, PhD
Research Sponsored by VA Pittsburgh Healthcare System
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up immediately following the 12-week intervention
Awards & highlights

Summary

This study will validate a predictive model that uses demographics, functional status, neurophysiology, neuroanatomy, and other potential biomarkers to predict the likelihood of a clinically significant change in impairment at the end of a robot assisted therapy intervention.The study will include magnetic resonance imaging (MRI), transcranial magnetic stimulation (TMS), and an arm exercise program consisting of robot-assisted exercise combined with functional arm exercise called transition to task training (TTT).

Eligible Conditions
  • Stroke
  • Nervous System Disorders
  • Brain Diseases
  • Central Nervous System Disorders
  • Cardiovascular Disease

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~immediately following the 12-week intervention
This trial's timeline: 3 weeks for screening, Varies for treatment, and immediately following the 12-week intervention for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Upper Extremity
Other study objectives
A Change in Brain Connections Assessed Via MRI of the Brain
A Change in Motor Evoked Potential During Transcranial Magnetic Stimulation of the Motor Cortex

Trial Design

1Treatment groups
Experimental Treatment
Group I: Robot + TTT ExerciseExperimental Treatment1 Intervention
All participants will be enrolled in this group to receive the same 60 minute study intervention consisting of wrist and shoulder-elbow robot training and TTT arm exercises.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Robot + TTT exercise
2016
N/A
~70

Find a Location

Who is running the clinical trial?

VA Pittsburgh Healthcare SystemLead Sponsor
33 Previous Clinical Trials
12,062 Total Patients Enrolled
2 Trials studying Stroke
77 Patients Enrolled for Stroke
University of PittsburghOTHER
1,769 Previous Clinical Trials
16,353,320 Total Patients Enrolled
28 Trials studying Stroke
2,900 Patients Enrolled for Stroke
George Wittenberg, PhDPrincipal InvestigatorUniversity of Pittsburgh
~0 spots leftby Sep 2025
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