Treatments for Depression (AIMS Trial)

Palo Alto (17 mi)

Overseen byStephen F Smagula, Ph.D

Age: 18+

Sex: Any

Travel: May be covered

Time Reimbursement: Varies

Trial Phase: N/A

Waitlist Available

Sponsor: University of Pittsburgh

No Placebo Group

Trial Summary

What is the purpose of this trial?This is a multi-site randomized control trial involving people age 55+ years who have current depression symptoms plus another suicide risk indicator (either current suicidal ideation or a past history of attempt). Our goal is evaluate which of two different approaches works best to improve things like trouble sleeping, bad moods, and any suicidality. Participants will complete diagnostic interviews, self-report scales, and wear an actigraphy device for the 8 weeks starting at the baseline visit.

Eligibility Criteria

This trial is for individuals aged 55 or older who are currently experiencing symptoms of depression and have a risk indicator for suicide, such as current suicidal thoughts or a past attempt. They must be able to complete interviews, self-reports, and wear an actigraphy device for sleep tracking over 8 weeks.

Inclusion Criteria

I have significant sleep problems.

I am 55 years old or older.

I have been on depression medication at the recommended dose for at least 2 weeks.

Exclusion Criteria

I am currently receiving inpatient care or considered at high risk for suicide.

I have been diagnosed with dementia or cannot give consent.

Treatment Details

The study compares two different approaches to see which one better improves sleep issues, mood, and suicidality in older adults with depression. Participants will receive either the usual treatment they would get from their healthcare provider or one of two active treatments being compared.

2Treatment groups

Experimental Treatment

Active Control

Group I: Active ConditionExperimental Treatment2 Interventions

Participants receive eight \~40 minute sessions (one per week) with a therapist/health coach. Specific information regarding the nature of the interventions is withheld to protect the scientific integrity of the study design.

Group II: Concealed Control InterventionActive Control2 Interventions