Trial Summary
What is the purpose of this trial?Patients with primary germ cell cancer of the testicles confined to the testis can avoid adjuvant treatment by entering a surveillance protocol. In the surveillance protocol, patients are followed for up to ten years with serial computed tomography scans to detect recurrence. Multiple CT scans expose patients to a significant amount of radiation, which may be associated with an increased risk of secondary malignancies. This study hypothesizes that low dose CT scans are as effective as standard dose CT scans in detecting disease recurrence in this setting and will significantly reduce radiation exposure in this group of patients.
Eligibility Criteria
This trial is for individuals with Stage I testicular cancer who are in their first year of surveillance for non-seminoma or within the first two years for seminoma. They must have a good performance status, meaning they're fully active or restricted in physically strenuous activity but can do light work.Inclusion Criteria
I have newly diagnosed testicular cancer with no signs it has spread.
I am fully active or restricted in physically strenuous activity but can do light work.
Exclusion Criteria
I do not have any health issues that would prevent me from following the study's procedures.
Treatment Details
The study is testing if low-dose computed tomography (LDCT) scans are as effective as standard CT scans at spotting cancer recurrence while reducing radiation exposure over up to ten years of patient follow-up.
1Treatment groups
Experimental Treatment
Group I: Patients with testicular germ cell cancerExperimental Treatment1 Intervention
Patients with testicular germ cell cancer who have either been newly diagnosed, or have stage I cancer already on surveillance program will undergo conventional and low dose CT. Based on the imaging, they may undergo a surveillance program using low-dose CT.
Find a clinic near you
Research locations nearbySelect from list below to view details:
University Health Network, Princess Margaret HospitalToronto, Canada
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Who is running the clinical trial?
University Health Network, TorontoLead Sponsor