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Medium or High Nicotine for Nicotine Addiction

N/A
Waitlist Available
Led By Neal Benowitz, MD
Research Sponsored by University of California, San Francisco
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up days 1-3 of each arm
Awards & highlights

Study Summary

This trial will study the effects of different nicotine levels in e-cigarettes on users' nicotine intake, exposure to harmful chemicals, and short-term cardiovascular health.

Eligible Conditions
  • Nicotine Addiction
  • Cardiovascular Risk

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~days 1-3 of each arm
This trial's timeline: 3 weeks for screening, Varies for treatment, and days 1-3 of each arm for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Cardiovascular Effects: Diastolic Blood Pressure
Cardiovascular Effects: Heart Rate
Cardiovascular Effects: Systolic Blood Pressure
+1 more
Secondary outcome measures
Vaping Topography: Inter-Puff Interval
Vaping Topography: Puff Duration
Vaping Topography: Puff Number

Trial Design

2Treatment groups
Experimental Treatment
Group I: Medium or High NicotineExperimental Treatment1 Intervention
The patient will participate in a standardized vaping session using either an electronic cigarette with 18 mg/ml nicotine e-liquid or a JUUL device with a JUUL e-liquid pod.
Group II: Low NicotineExperimental Treatment1 Intervention
Using an electronic cigarette, the patient will participate in a standardized vaping session using 3 mg/ml nicotine e-liquid.

Find a Location

Who is running the clinical trial?

University of California, San FranciscoLead Sponsor
2,517 Previous Clinical Trials
15,241,029 Total Patients Enrolled
2 Trials studying Nicotine Addiction
991 Patients Enrolled for Nicotine Addiction
National Institute on Drug Abuse (NIDA)NIH
2,485 Previous Clinical Trials
2,622,380 Total Patients Enrolled
15 Trials studying Nicotine Addiction
2,130 Patients Enrolled for Nicotine Addiction
Neal Benowitz, MDPrincipal InvestigatorUniversity of California, San Francisco
2 Previous Clinical Trials
38 Total Patients Enrolled
~0 spots leftby Jun 2025
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