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A Trial of Non-invasive Stimulation in Cervical Dystonia

N/A
Waitlist Available
Led By Mandar Jog, MD
Research Sponsored by Western University, Canada
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
* Patients with cervical dystonia who are already on 3 monthly BoNT-A therapy but the effect of BoNT-A is wearing off in 8 weeks.
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 3 months

Summary

This trial tests a gentle electrical current treatment for patients with cervical dystonia who are not fully satisfied with their current injections. The goal is to improve brain function and movement control by normalizing brain activity.

Eligible Conditions
  • Torticollis

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~3 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Changes in Network fragmentation using Quantitative Electroencephalography (qEEG)
Changes in Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS).
Kinematic changes in angular deviation and amplitude measures

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Real NIBSExperimental Treatment1 Intervention
In Real NIBS arm, active Noninvasive brain stimulation (NIBS) will be given for 20 mins.
Group II: Sham NIBSPlacebo Group1 Intervention
In Sham NIBS arm, sham Noninvasive brain stimulation (NIBS) will be given for 20 mins.

Find a Location

Who is running the clinical trial?

Western University, CanadaLead Sponsor
254 Previous Clinical Trials
59,271 Total Patients Enrolled
2 Trials studying Torticollis
72 Patients Enrolled for Torticollis
Mandar Jog, MDPrincipal InvestigatorLondon Health Sciences Centre
7 Previous Clinical Trials
459 Total Patients Enrolled
1 Trials studying Torticollis
39 Patients Enrolled for Torticollis
~2 spots leftby Dec 2025
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