Genetic Study for Coronary Artery Dissection
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial focuses on understanding the long-term effects of Spontaneous Coronary Artery Dissection (SCAD). Researchers observe patients who have experienced an acute coronary syndrome, such as a heart attack or severe chest pain, and have confirmed SCAD through specific heart imaging tests. The trial includes a genetic sub-study to determine if hereditary factors play a role. It suits those hospitalized for SCAD without significant blockage from coronary artery disease. As an unphased trial, this study offers a unique opportunity to contribute to groundbreaking research that may enhance future SCAD treatments.
Do I need to stop my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications.
Why are researchers excited about this trial?
Researchers are excited about this genetic sub-study for SCAD (Spontaneous Coronary Artery Dissection) because it aims to uncover genetic factors that might predispose individuals to this condition. Unlike standard treatments that focus on managing symptoms or repairing arteries, this study dives into the genetic makeup, which could lead to personalized medicine approaches. By identifying specific genetic markers, there is potential to predict risk better and tailor prevention strategies, which is a significant leap forward in managing SCAD compared to current treatment methods.
Who Is on the Research Team?
Jacqueline Saw, MD
Principal Investigator
Cardiology Research UBC / Vancouver General Hospital
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline Assessment
Detailed baseline demographics, targeted history for precipitating stressors and predisposing conditions, and investigations for predisposing conditions
In-hospital Observation
Monitoring of in-hospital CV outcomes including death, MI, CVA, unplanned revascularization, and heart failure
Short-term Follow-up
Assessment of arterial healing post SCAD via angiographic healing
Long-term Follow-up
Participants are monitored for long-term CV outcomes including death, MI, CVA, revascularization, and heart failure
What Are the Treatments Tested in This Trial?
Interventions
- Genetic sub-study
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
Single group observational study
Find a Clinic Near You
Who Is Running the Clinical Trial?
Cardiology Research UBC
Lead Sponsor
John GB Mancini, MD
Collaborator
Karin Humphries, DSc
Collaborator
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