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Targeted Therapy

Treatment for Diffuse Intrinsic Pontine Glioma

N/A
Waitlist Available
Research Sponsored by Nationwide Children's Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be younger than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 years
Awards & highlights

Summary

The goal of this study is to perform genetic sequencing on brain tumors from children, adolescents, and young adult patients who have been newly diagnosed with a high-grade glioma. This molecular profiling will decide if patients are eligible to participate in a subsequent treatment-based clinical trial based on the genetic alterations identified in their tumor.

Eligible Conditions
  • Diffuse Intrinsic Pontine Glioma
  • Brain Tumor
  • Anaplastic Astrocytoma
  • Diffuse Midline Glioma
  • Gliomas
  • Glioblastoma

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Feasibility of molecular profiling and enrollment to a TarGeT treatment protocol
Molecular profiling
Secondary outcome measures
Biobanking
Genomic Research
Germline susceptibility testing

Find a Location

Who is running the clinical trial?

Nationwide Children's HospitalLead Sponsor
347 Previous Clinical Trials
5,228,776 Total Patients Enrolled
7 Trials studying Diffuse Intrinsic Pontine Glioma
439 Patients Enrolled for Diffuse Intrinsic Pontine Glioma
Maryam Fouladi, MDStudy ChairNationwide Children's Hospital
11 Previous Clinical Trials
2,015 Total Patients Enrolled
8 Trials studying Diffuse Intrinsic Pontine Glioma
1,901 Patients Enrolled for Diffuse Intrinsic Pontine Glioma
Margot Lazow, MDStudy DirectorNationwide Children's Hospital
2 Previous Clinical Trials
164 Total Patients Enrolled
2 Trials studying Diffuse Intrinsic Pontine Glioma
164 Patients Enrolled for Diffuse Intrinsic Pontine Glioma
~300 spots leftby Jun 2029
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