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Exploratory Study on Effect of Whitening Agent With Emulsion Gel in Xerostomic Population

N/A
Waitlist Available
Led By Mabi Singh, DMD, MS
Research Sponsored by Tufts University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up visit 1 and visit 2 pre and post saliva production in day 1 and day 7
Awards & highlights
No Placebo-Only Group

Summary

This trial investigates whether a teeth whitening gel can help reduce dry mouth symptoms. The gel is thought to stay in the mouth longer and stimulate saliva production. The study focuses on people with dry mouth due to various causes, aiming to see if the gel can improve their condition.

Eligible Conditions
  • Dry Mouth

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~visit 1 and visit 2 pre and post saliva production in day 1 and day 7
This trial's timeline: 3 weeks for screening, Varies for treatment, and visit 1 and visit 2 pre and post saliva production in day 1 and day 7 for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Subjective Perception of Mouth Dryness
Secondary study objectives
Change in Saliva Production Measured in ml/Min
Perceived Sensitivity of Teeth Between Visit 1 and 2

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: All ParticipantsExperimental Treatment1 Intervention
This is a single arm study. All subjects enrolled will be apart of the experimental group. Subjects in this group will use Crest Whitening Emulsions on their teeth up to 4 times a day for 7 days in order for the study team to evaluate if the study intervention product increases saliva production in this Xerostomic population.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Crest Whitening Emulsions
2021
N/A
~30

Find a Location

Who is running the clinical trial?

Procter and GambleIndustry Sponsor
147 Previous Clinical Trials
76,673 Total Patients Enrolled
2 Trials studying Dry Mouth
159 Patients Enrolled for Dry Mouth
Tufts UniversityLead Sponsor
270 Previous Clinical Trials
594,866 Total Patients Enrolled
Mabi Singh, DMD, MSPrincipal InvestigatorTufts University School of Dental Medicine
~6 spots leftby Dec 2025