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Children's Mercy Hospital

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Kansas City, Missouri 64108

Global Leader in Cancer

Global Leader in Leukemia

Conducts research for Neuroblastoma

Conducts research for Acute Lymphoblastic Leukemia

Conducts research for Brain Tumor

841 reported clinical trials

48 medical researchers

Photo of Children's Mercy Hospital in Kansas CityPhoto of Children's Mercy Hospital in Kansas CityPhoto of Children's Mercy Hospital in Kansas City

Summary

Children's Mercy Hospital is a medical facility located in Kansas City, Missouri. This center is recognized for care of Cancer, Leukemia, Neuroblastoma, Acute Lymphoblastic Leukemia, Brain Tumor and other specialties. Children's Mercy Hospital is involved with conducting 841 clinical trials across 1,088 conditions. There are 48 research doctors associated with this hospital, such as Keith J. August, Kevin F. Ginn, John Anderson, MD, and Mark Clements, MD, PhD.

Area of expertise

1

Cancer

Global Leader

Children's Mercy Hospital has run 80 trials for Cancer. Some of their research focus areas include:

Stage IV
Stage I
Stage II
2

Leukemia

Global Leader

Children's Mercy Hospital has run 73 trials for Leukemia. Some of their research focus areas include:

NTRK1 positive
NTRK positive
ABL-class fusions positive

Top PIs

Clinical Trials running at Children's Mercy Hospital

Brain Tumor

Cancer

Testicular cancer

Neuroblastoma

Wilms Tumor

Chronic Kidney Disease

Burkitt Lymphoma

Lazy Eye

Leukemia

Brain Cancer

Image of trial facility.

Selumetinib vs. Chemotherapy

for Brain Cancer

This trial is comparing a new drug, selumetinib, with standard chemotherapy to treat patients with a specific type of brain tumor. The patients do not have a certain genetic mutation and are not affected by a genetic disorder. Selumetinib works by blocking enzymes needed for tumor growth, while the standard drugs kill or stop tumor cells from dividing.

Recruiting

2 awards

Phase 3

Image of trial facility.

Selinexor + Radiation

for Brain Cancer

This trial tests the safety and effectiveness of combining selinexor with radiation therapy in children and young adults with aggressive brain tumors. Selinexor is a drug that blocks a protein to stop cancer cells from growing. The study aims to find the best dose and see if this combination can shrink tumors.

Recruiting

1 award

Phase 1 & 2

1 criteria

Image of trial facility.

Lower Radiotherapy Dose

for Brain Tumors

This phase II trial studies how well lower dose radiotherapy after chemotherapy (Carboplatin \& Etoposide) works in treating children with central nervous system (CNS) germinomas. Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill cancer cells and shrink tumors. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping or slowing the growth of tumor cells. Etoposide is in a class of medications known as podophyllotoxin derivatives. It blocks a certain enzyme needed for cell division and DNA repair and may kill cancer cells. Researchers want to see if lowering the dose of standard radiotherapy (RT) after chemotherapy can help get rid of CNS germinomas with fewer long-term side effects.

Recruiting

1 award

Phase 2

10 criteria

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