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Saint Joseph

Heartland Regional Medical Center

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Saint Joseph, Missouri 64506

Global Leader in Breast Cancer

Global Leader in Lung Cancer

Conducts research for Cancer

Conducts research for Breast cancer

Conducts research for Ovarian Cancer

336 reported clinical trials

2 medical researchers

Photo of Heartland Regional Medical Center in Saint JosephPhoto of Heartland Regional Medical Center in Saint JosephPhoto of Heartland Regional Medical Center in Saint Joseph

Summary

Heartland Regional Medical Center is a medical facility located in Saint Joseph, Missouri. This center is recognized for care of Breast Cancer, Lung Cancer, Cancer, Breast cancer, Ovarian Cancer and other specialties. Heartland Regional Medical Center is involved with conducting 336 clinical trials across 465 conditions. There are 2 research doctors associated with this hospital, such as Jay W Carlson and Rony Abou-Jawde, MD.

Area of expertise

1

Breast Cancer

Global Leader

Heartland Regional Medical Center has run 60 trials for Breast Cancer. Some of their research focus areas include:

HER2 negative
Stage IV
ER positive
2

Lung Cancer

Global Leader

Heartland Regional Medical Center has run 49 trials for Lung Cancer. Some of their research focus areas include:

Stage IV
Stage II
Stage I

Top PIs

Clinical Trials running at Heartland Regional Medical Center

Breast Cancer

Lung Cancer

Bladder Cancer

Ovarian Cancer

Breast cancer

Cancer

Colorectal Cancer

Prostate Cancer

Melanoma

Esophageal cancer

Image of trial facility.

Shorter Chemo-Immunotherapy Without Anthracyclines

for Breast Cancer

This phase III trial compares the effects of shorter chemotherapy (chemo)-immunotherapy without anthracyclines to usual chemo-immunotherapy for the treatment of early-stage triple negative breast cancer. Paclitaxel is in a class of medications called anti-microtubule agents. It stops cancer cells from growing and dividing and may kill them. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping or slowing the growth of cancer cells. Cyclophosphamide is in a class of medications called alkylating agents. It works by damaging the cell's deoxyribonucleic acid (DNA) and may kill cancer cells. It may also lower the body's immune response. Docetaxel is in a class of medications called taxanes. It stops cancer cells from growing and dividing and may kill them. Doxorubicin is an anthracycline chemotherapy drug that damages DNA and may kill cancer cells. Pembrolizumab may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Shorter treatment without anthracycline chemotherapy may work the same as the usual anthracycline chemotherapy treatment for early-stage triple negative breast cancer.

Recruiting

2 awards

Phase 3

47 criteria

Image of trial facility.

Mindfulness Approaches

for Living After Breast Cancer

NRG-CC015 is a prospective, randomized phase III clinical trial to evaluate the efficacy of two distinct digital approaches for delivering a mindfulness-based intervention: a live, instructor-led version delivered over Zoom (MAPs LO), and an app-based, self-paced version (MAPs App). Participants will include younger breast cancer survivors (BCS) who were diagnosed with breast cancer at or before age 50 years, have completed their primary cancer treatment (i.e., surgery, radiation, and/or chemotherapy) at least 6 months earlier, and report elevated depressive symptoms.

Recruiting

2 awards

Phase 3

5 criteria

Image of trial facility.

HER2-Targeted Therapy

for Breast Cancer

This phase III trial compares 6 months of human epidermal growth factor receptor 2 (HER2)-targeted therapy to 12 months of HER2-targeted therapy for the treatment of HER2-positive (+) breast cancer in patients that had a pathologic complete response (pCR) after preoperative (neoadjuvant) chemotherapy with trastuzumab. Trastuzumab and pertuzumab are monoclonal antibodies and forms of targeted therapy that attach to a receptor protein called HER2. HER2 is found on some cancer cells. When trastuzumab or pertuzumab attach to HER2, the signals that tell the cells to grow are blocked and the tumor cell may be marked for destruction by the body's immune system. Giving 6 months of HER2-targeted therapy may work better than giving 12 months for the treatment of HER2+ breast cancer in patients that had a pCR after neoadjuvant chemotherapy with trastuzumab.

Recruiting

2 awards

Phase 3

5 criteria

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