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MediSearch Clinical Trials
Claim this profileSaint Joseph, Missouri 64506
Global Leader in Atopic Dermatitis
Global Leader in Eczema
Conducts research for Psoriasis
Conducts research for Acne
Conducts research for Plaque Psoriasis
57 reported clinical trials
1 medical researcher
Summary
MediSearch Clinical Trials is a medical facility located in Saint Joseph, Missouri. This center is recognized for care of Atopic Dermatitis, Eczema, Psoriasis, Acne, Plaque Psoriasis and other specialties. MediSearch Clinical Trials is involved with conducting 57 clinical trials across 34 conditions. There are 1 research doctors associated with this hospital, such as Melody Stone.Top PIs
Clinical Trials running at MediSearch Clinical Trials
Atopic Dermatitis
Vitiligo
Hidradenitis Suppurativa
Alopecia Areata
Eczema
Hair Loss
Pathology
Systemic Lupus Erythematosus
Prurigo
Skin Diseases
Upadacitinib
for Eczema
Atopic dermatitis (AD) is a skin condition that may cause a rash and itching due to inflammation of the skin. Therapies spread over the skin may not be enough to control the AD in trial participants who require systemic anti-inflammatory treatment. This study aims to provide data on the efficacy and safety of upadacitinib at different doses in adult participants with moderate to severe AD. Upadacitinib is an approved drug for the treatment of moderate to severe atopic dermatitis (AD). This study is conducted in 2 periods. During Period 1, participants are randomly assigned into 1 of 2 groups called treatment arms to receive upadacitinib Dose A or dupilumab Dose A. Based on the participants response to upadacitinib Dose A, they may have their dose increased to upadacitinib Dose B after 2 weeks. In Period 2, participants that completed Period 1 will either remain on their assigned dose or be reassigned to a different dose based on their Eczema Area and Severity Index (EASI) response. Approximately 300 adult participants ages 18 to 64 with moderate to severe AD who are current users of dupilumab and had a history of inadequate response to dupilumab will be enrolled at up to 94 sites worldwide. The study is comprised of a 35-day Screening Period, an 8-week Open-Label Period 1 and a 24-week Open-Label Period 2 for participants that completed Period 1. Participants will receive upadacitinib oral tablets once daily or dupilumab subcutaneous (SC) injection every other week for 32 weeks and followed for 30 days. There may be higher treatment burden for participants in this trial compared to their standard of care. Participants will attend regular visits during the study at a hospital or clinic. The effect of the treatment will be checked by medical assessments, blood tests, checking for side effects and completing questionnaires.
Recruiting2 awards Phase 32 criteria
Rocatinlimab
for Atopic Dermatitis
This trial is testing a medication called rocatinlimab to see if it works and is safe for teenagers. The medication can be used by itself or with other treatments. It aims to help by interacting with the immune system.
Recruiting1 award Phase 38 criteria
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Frequently asked questions
What kind of research happens at MediSearch Clinical Trials?
MediSearch Clinical Trials is a medical facility located in Saint Joseph, Missouri. This center is recognized for care of Atopic Dermatitis, Eczema, Psoriasis, Acne, Plaque Psoriasis and other specialties. MediSearch Clinical Trials is involved with conducting 57 clinical trials across 34 conditions. There are 1 research doctors associated with this hospital, such as Melody Stone.