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Ohio State University

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Columbus, Ohio 43210

Global Leader in Heart Failure

Global Leader in Cancer

Conducts research for Breast Cancer

Conducts research for Stroke

Conducts research for Lung Cancer

1255 reported clinical trials

214 medical researchers

Photo of Ohio State University in ColumbusPhoto of Ohio State University in Columbus

Summary

Ohio State University is a medical facility located in Columbus, Ohio. This center is recognized for care of Heart Failure, Cancer, Breast Cancer, Stroke, Lung Cancer and other specialties. Ohio State University is involved with conducting 1,255 clinical trials across 2,083 conditions. There are 214 research doctors associated with this hospital, such as Floor Backes, MD, Alice Mims, Uma Borate, MD, and Michael V Knopp, MD, PhD.

Area of expertise

1

Heart Failure

Global Leader

Ohio State University has run 121 trials for Heart Failure. Some of their research focus areas include:

Stage III
BAROSTIM
Stage II
2

Cancer

Global Leader

Ohio State University has run 109 trials for Cancer. Some of their research focus areas include:

Stage IV
Stage III
FGFR3 positive

Top PIs

Clinical Trials running at Ohio State University

Stroke

Melanoma

Cancer

Lung Cancer

Facioscapulohumeral muscular dystrophy

Skin Cancer

Alzheimer's Disease

Atrial Fibrillation

Facioscapulohumeral Muscular Dystrophy

Age-Related Macular Degeneration

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Low-Dose Colchicine

for Peripheral Artery Disease

The Low dose ColchicinE in pAtients with peripheral Artery DiseasE to address residual vascular Risk (LEADER-PAD) trial will evaluate if anti-inflammatory therapy with colchicine will reduce vascular events in patients with symptomatic peripheral artery disease.

Recruiting

3 awards

Phase 3

3 criteria

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Sovateltide

for Stroke

Extensive research is being conducted in search of neuroprotective agents for possible use in the acute phase of stroke and agents that can be used for neurorepair in later stages of stroke. Several trials have been conducted and are in progress using different pharmacological agents, but none of the studies involve the stimulation of ETB receptors to treat cerebral ischemic stroke. Sovateltide (IRL-1620, PMZ-1620) has been effective in animal models of cerebral ischemic stroke. Its safety and tolerability have been demonstrated in a human phase I study with 7 subjects. Clinical phase II and III results indicate that sovateltide is a novel, first-in-class, highly effective drug candidate for treating cerebral ischemic stroke. Safety and significant efficacy in improving the National Institutes of Health Stroke Scale (NIHSS), Modified Rankin scale (mRS), and Barthel index (BI) obtained in phase II and III studies in patients with cerebral ischemic stroke in India are convincing and encouraged us to investigate its safety and efficacy in cerebral ischemic stroke patients in the United States. Therefore, the plan is to conduct a phase III clinical study to evaluate the safety and efficacy of sovateltide therapy along with standard of care in patients of acute ischemic stroke.

Recruiting

2 awards

Phase 3

3 criteria

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Anticoagulation + Antiplatelet Therapy

for Post-Operative Atrial Fibrillation

The primary objective of this study is to evaluate the effectiveness (prevention of thromboembolic events) and safety (major bleeding) of adding oral anticoagulation (OAC) to background antiplatelet therapy in patients who develop new-onset post-operative atrial fibrillation (POAF) after isolated coronary artery bypass graft (CABG) surgery. All patients with a qualifying POAF event, who decline randomization, will be offered the option of enrollment in a parallel registry that captures their baseline risk profile and their treatment strategy in terms of anticoagulants or antiplatelets received. These patients will also be asked to fill out a brief decliner survey.

Recruiting

2 awards

Phase 3

2 criteria

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