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Riley Hospital for Children

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Indianapolis, Indiana 46202
Global Leader in Leukemia
Global Leader in Recurrence
Conducts research for Tumors
Conducts research for Lymphoma
Conducts research for Cystic Fibrosis
551 reported clinical trials
39 medical researchers
Photo of Riley Hospital for Children in IndianapolisPhoto of Riley Hospital for Children in IndianapolisPhoto of Riley Hospital for Children in Indianapolis

Summary

Riley Hospital for Children is a medical facility located in Indianapolis, Indiana. This center is recognized for care of Leukemia, Recurrence, Tumors, Lymphoma, Cystic Fibrosis and other specialties. Riley Hospital for Children is involved with conducting 551 clinical trials across 739 conditions. There are 39 research doctors associated with this hospital, such as Sandeep Batra, MD, Brian Weiss, MD, Melissa Bear, and Linda DiMeglio, MD.

Area of expertise

1Leukemia
Global Leader
Riley Hospital for Children has run 76 trials for Leukemia. Some of their research focus areas include:
Stage II
Philadelphia chromosome positive
CD22 positive
2Recurrence
Global Leader
Riley Hospital for Children has run 70 trials for Recurrence. Some of their research focus areas include:
Stage IV
M1b
BRAF positive

Top PIs

Clinical Trials running at Riley Hospital for Children

Brain Tumor
Osteosarcoma
Acute Myeloid Leukemia
Lymphoma
Non-Hodgkin's Lymphoma
Leukemia
Acute Lymphoblastic Leukemia
Tumors
Germ Cell Tumors
Recurrence
Image of trial facility.

Selumetinib vs. Chemotherapy

for Brain Cancer

This trial is comparing a new drug, selumetinib, with standard chemotherapy to treat patients with a specific type of brain tumor. The patients do not have a certain genetic mutation and are not affected by a genetic disorder. Selumetinib works by blocking enzymes needed for tumor growth, while the standard drugs kill or stop tumor cells from dividing.
Recruiting2 awards Phase 3
Image of trial facility.

Selumetinib vs Carboplatin/Vincristine

for Brain Cancer

This phase III trial studies if selumetinib works just as well as the standard treatment with carboplatin/vincristine (CV) for subjects with NF1-associated low grade glioma (LGG), and to see if selumetinib is better than CV in improving vision in subjects with LGG of the optic pathway (vision nerves). Selumetinib is a drug that works by blocking some enzymes that low-grade glioma tumor cells need for their growth. This results in killing tumor cells. Drugs used as chemotherapy, such as carboplatin and vincristine, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. It is not yet known whether selumetinib works better in treating patients with NF1-associated low-grade glioma compared to standard therapy with carboplatin and vincristine.
Recruiting2 awards Phase 328 criteria
Image of trial facility.

Selumetinib + Vinblastine

for Low-Grade Glioma

This phase III trial investigates the best dose of vinblastine in combination with selumetinib and the benefit of adding vinblastine to selumetinib compared to selumetinib alone in treating children and young adults with low-grade glioma (a common type of brain cancer) that has come back after prior treatment (recurrent) or does not respond to therapy (progressive). Selumetinib is a drug that works by blocking a protein that lets tumor cells grow without stopping. Vinblastine blocks cell growth by stopping cell division and may kill cancer cells. Giving selumetinib in combination with vinblastine may work better than selumetinib alone in treating recurrent or progressive low-grade glioma.
Recruiting2 awards Phase 339 criteria

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Frequently asked questions

What kind of research happens at Riley Hospital for Children?
Riley Hospital for Children is a medical facility located in Indianapolis, Indiana. This center is recognized for care of Leukemia, Recurrence, Tumors, Lymphoma, Cystic Fibrosis and other specialties. Riley Hospital for Children is involved with conducting 551 clinical trials across 739 conditions. There are 39 research doctors associated with this hospital, such as Sandeep Batra, MD, Brian Weiss, MD, Melissa Bear, and Linda DiMeglio, MD.
Where is Riley Hospital for Children located?
Riley Hospital for Children at IU Health is situated at 705 Riley Hospital Dr, Indianapolis, IN 46202.
Who should I call to ask about financial aid or insurance network?
For financial assistance and insurance inquiries at Riley Hospital for Children, contact their department at 888.531.3004 (Monday-Friday, 8am - 4:30pm) or via email at financialcounseling@iuhealth.org. They provide support through Medicaid, IU Health Financial Assistance, and other health coverage programs. Indiana residents receiving care through emergency services, direct physician admission, or hospital transfers may qualify for extra assistance based on financial hardship.
What insurance does Riley Hospital for Children accept?
Riley Hospital for Children accepts a wide range of insurance plans, including Medicaid, The Healthy Indiana Plan (HIP), Hoosier Healthwise (HHW), COBRA, and private insurance plans such as Aetna, Anthem PPO/HMO, Blue Cross and Blue Shield, CIGNA HealthCare PPO/HMO, Humana ChoiceCare, and UnitedHealthcare. They participate in most major health plans in Indiana. Patients are advised to review their health plan provider directory and consult with their insurance company to confirm coverage.
What awards or recognition has Riley Hospital for Children received?
Riley Hospital for Children, located in Indianapolis, Indiana, is celebrated for its outstanding pediatric care, ranking among the nation's top children's hospitals in all 10 pediatric specialties according to U.S. News & World Report. It is also designated as a Level I Children's Surgery Center by the American College of Surgeons, showcasing its capability to offer comprehensive surgical care for infants and children with complex conditions.