Dr. Melissa Bear
Claim this profileRiley Hospital for Children
Studies Cancer
Studies Uterine Tumors
14 reported clinical trials
26 drugs studied
Area of expertise
1Cancer
Stage IV
APC negative
FBXW7 negative
2Uterine Tumors
Stage IV
APC negative
FBXW7 negative
Affiliated Hospitals
Clinical Trials Melissa Bear is currently running
CBL0137
for Cancer
This trial tests CBL0137, a drug that blocks signals inside cancer cells, in patients whose solid tumors, including CNS tumors or lymphoma, have returned or not responded to treatment. By interfering with the cells' internal communication, the drug aims to stop their growth and cause them to die. CBL0137, also known as Curaxin, has shown antitumor activity in multiple cancers, including glioblastoma, renal cell carcinoma, melanoma, neuroblastoma, and small cell lung cancer.
Recruiting1 award Phase 1 & 213 criteria
Chemotherapy
for Wilms Tumor
This phase II trial studies how well combination chemotherapy works in treating patients with newly diagnosed stage II-IV diffuse anaplastic Wilms tumors (DAWT) or favorable histology Wilms tumors (FHWT) that have come back (relapsed). Drugs used in chemotherapy regimens such as UH-3 (vincristine, doxorubicin, cyclophosphamide, carboplatin, etoposide, and irinotecan) and ICE/Cyclo/Topo (ifosfamide, carboplatin, etoposide, cyclophosphamide, and topotecan) work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. This trial may help doctors find out what effects, good and/or bad, regimen UH-3 has on patients with newly diagnosed DAWT and standard risk relapsed FHWT (those treated with only 2 drugs for the initial WT) and regimen ICE/Cyclo/Topo has on patients with high and very high risk relapsed FHWT (those treated with 3 or more drugs for the initial WT).
Recruiting1 award Phase 212 criteria
More about Melissa Bear
Clinical Trial Related9 years of experience running clinical trials · Led 14 trials as a Principal Investigator · 5 Active Clinical TrialsTreatments Melissa Bear has experience with
- Irinotecan
- Cyclophosphamide
- Ramucirumab
- Abemaciclib
- Temozolomide
- Vincristine
Breakdown of trials Melissa Bear has run
Cancer
Uterine Tumors
Relapse
Solid Tumors
Other Doctors you might be interested in
Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Melissa Bear specialize in?
Melissa Bear focuses on Cancer and Uterine Tumors. In particular, much of their work with Cancer has involved Stage IV patients, or patients who are APC negative.
Is Melissa Bear currently recruiting for clinical trials?
Yes, Melissa Bear is currently recruiting for 4 clinical trials in Indianapolis Indiana. If you're interested in participating, you should apply.
Are there any treatments that Melissa Bear has studied deeply?
Yes, Melissa Bear has studied treatments such as Irinotecan, Cyclophosphamide, Ramucirumab.
What is the best way to schedule an appointment with Melissa Bear?
Apply for one of the trials that Melissa Bear is conducting.
What is the office address of Melissa Bear?
The office of Melissa Bear is located at: Riley Hospital for Children, Indianapolis, Indiana 46202-5225 United States. This is the address for their practice at the Riley Hospital for Children.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.