Dr. Melissa Bear
Claim this profileRiley Hospital for Children
Studies Tumors
Studies Recurrence
14 reported clinical trials
26 drugs studied
Area of expertise
1Tumors
Stage IV
APC negative
FBXW7 negative
2Recurrence
Stage IV
APC negative
FBXW7 negative
Affiliated Hospitals
Clinical Trials Melissa Bear is currently running
CBL0137
for Cancer
This trial tests CBL0137, a drug that blocks signals inside cancer cells, in patients whose solid tumors, including CNS tumors or lymphoma, have returned or not responded to treatment. By interfering with the cells' internal communication, the drug aims to stop their growth and cause them to die. CBL0137, also known as Curaxin, has shown antitumor activity in multiple cancers, including glioblastoma, renal cell carcinoma, melanoma, neuroblastoma, and small cell lung cancer.
Recruiting1 award Phase 1 & 213 criteria
Abemaciclib + Chemotherapy
for Sarcoma
This trial is testing whether adding a new drug called abemaciclib to standard cancer treatments can help children and young adults with Ewing's sarcoma that has come back or did not respond to previous treatments. Abemaciclib works by blocking proteins that help cancer cells grow, which may slow down or stop the tumor. Participation could last several months or more, depending on individual responses.
Recruiting1 award Phase 2
More about Melissa Bear
Clinical Trial Related8 years of experience running clinical trials · Led 14 trials as a Principal Investigator · 6 Active Clinical TrialsTreatments Melissa Bear has experience with
- Irinotecan
- Ramucirumab
- Cyclophosphamide
- Abemaciclib
- Temozolomide
- Vincristine
Breakdown of trials Melissa Bear has run
Tumors
Recurrence
Solid Tumors
Sarcoma
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Melissa Bear specialize in?
Melissa Bear focuses on Tumors and Recurrence. In particular, much of their work with Tumors has involved Stage IV patients, or patients who are APC negative.
Is Melissa Bear currently recruiting for clinical trials?
Yes, Melissa Bear is currently recruiting for 5 clinical trials in Indianapolis Indiana. If you're interested in participating, you should apply.
Are there any treatments that Melissa Bear has studied deeply?
Yes, Melissa Bear has studied treatments such as Irinotecan, Ramucirumab, Cyclophosphamide.
What is the best way to schedule an appointment with Melissa Bear?
Apply for one of the trials that Melissa Bear is conducting.
What is the office address of Melissa Bear?
The office of Melissa Bear is located at: Riley Hospital for Children, Indianapolis, Indiana 46202-5225 United States. This is the address for their practice at the Riley Hospital for Children.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.