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University Health Network

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TORONTO, Ontario M5G 2C4
Global Leader in Cancer
Global Leader in Prostate Cancer
Conducts research for Lung Cancer
Conducts research for Infections
Conducts research for Coronavirus
541 reported clinical trials
60 medical researchers
Photo of University Health Network in TORONTOPhoto of University Health Network in TORONTOPhoto of University Health Network in TORONTO

Summary

University Health Network is a medical facility located in TORONTO, Ontario. This center is recognized for care of Cancer, Prostate Cancer, Lung Cancer, Infections, Coronavirus and other specialties. University Health Network is involved with conducting 541 clinical trials across 583 conditions. There are 60 research doctors associated with this hospital, such as Lillian Siu, MD, Marcus Butler, Anna Spreafico, MD PhD, and John Kuruvilla, MD.

Area of expertise

1Cancer
Global Leader
University Health Network has run 40 trials for Cancer. Some of their research focus areas include:
Stage IV
TP53 positive
HER2 positive
2Prostate Cancer
Global Leader
University Health Network has run 32 trials for Prostate Cancer. Some of their research focus areas include:
Stage IV

Top PIs

Clinical Trials running at University Health Network

Cancer
Breast Cancer
Prostate Cancer
Brain Tumor
Stroke
Bladder Cancer
Lymphoma
Acute Leukemia
Non-Small Cell Lung Cancer
Depression
Image of trial facility.

Stopping Heart Medications

for Cancer Survivors

Cancer therapy-related cardiac dysfunction (CTRCD) is when the heart's ability to pump oxygenated blood to the body is compromised. It is a side effect of cancer therapy which can occur as commonly as in 1 in 5 patients. When this occurs, heart failure medications are started to protect the heart from progressing to heart failure. With early detection and treatment, heart function recovers to normal in \>80% of patients. Unfortunately, heart failure medications are associated with an undesirable long-term pill burden, financial costs, and side-effects (e.g., dizziness and fatigue). As a result, cancer survivors frequently ask if they can safely stop their heart failure medications once their heart function has returned to normal. Currently there is no scientific evidence in this area of Cardio-Oncology. To address this knowledge gap, the investigators have designed a randomized control trial to assess the safety of stopping heart failure medication in patients with CTRCD and recovered heart function. The investigators will enrol patients who have completed their cancer therapy and are on heart medications for their CTRCD, which has now normalized. The investigators will randomize patients with no other reasons to continue heart failure medications (e.g., kidney disease) to continuing or stopping their heart medications safely. All patients will undergo a cardiac MRI at baseline, 1 and 5 years with safety assessments at 6-8 weeks, 6 and 9 months and 3 and 5 years. The investigators will determine if stopping medications is non-inferior to continuing medications by counting the numbers of patients who develop heart dysfunction by 1 year in each group.
Recruiting3 awards Phase 4
Image of trial facility.

IVLP with Oxaliplatin

for Colorectal Cancer Spread to Lungs

This trial is testing a new method of delivering chemotherapy directly into the lungs during surgery to treat patients with colorectal cancer that has spread to the lungs. The goal is to kill cancer cells in the lung while minimizing side effects to other organs. The study will determine the safest dose of the chemotherapy drug oxaliplatin when delivered using this method.
Recruiting1 award Phase 1
Image of trial facility.

RP-6306 Combination Therapy

for Cancer

This trial is testing RP-6306, a new drug, to see if it can help treat cancer when used with standard treatments. It focuses on patients with specific biomarkers to see if they respond better. The drug works by blocking a protein that helps cancer cells grow.
Recruiting1 award Phase 2

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Frequently asked questions

What kind of research happens at University Health Network?
University Health Network is a medical facility located in TORONTO, Ontario. This center is recognized for care of Cancer, Prostate Cancer, Lung Cancer, Infections, Coronavirus and other specialties. University Health Network is involved with conducting 541 clinical trials across 583 conditions. There are 60 research doctors associated with this hospital, such as Lillian Siu, MD, Marcus Butler, Anna Spreafico, MD PhD, and John Kuruvilla, MD.
Where is University Health Network located?
**University Health Network Hospital Location and Access:** - **Address:** 200 Elizabeth St, Downtown Toronto, ON. Located near the intersection of College Street and University Avenue. - **Public Transportation:** Accessible via Queen's Park subway station on Line 1 (Yonge-University-Spadina line), 506 Carlton, and 505 Dundas streetcars. - **Parking:** Available at the hospital. Note: Street parking is restricted.
Who should I call to ask about financial aid or insurance network?
For financial assistance at University Health Network: - Contact by phone: 888.531.3004 (Monday-Friday, 8am - 4:30pm) or use the online form. - For insurance inquiries: Call 210-358-3350 or use the Contact Us form. Verify insurance acceptance with your provider. - Billing support: Call 210-358-3260. - Apply for financial assistance through the University Health Financial Assistance Program, considering residency, income, and family size.
What insurance does University Health Network accept?
The University Health Network (UHN) accepts a wide range of insurance plans, including Medicare, Medicaid/Health First CO, and many others, and strives to be in-network for most insurance plans. However, patients are advised to confirm network status and coverage details with their insurance provider and clinic before receiving services. Similarly, CU Medicine and University Hospitals Lake West Medical Center accept most major insurance plans, but it is crucial for patients to verify specific provider participation and in-network status with their insurance carrier prior to their visit to avoid unexpected out-of-pocket expenses.
What awards or recognition has University Health Network received?
University Health Network (UHN) in Toronto, Ontario, Canada, specializes in health research and patient care across various domains including cancer, cardiovascular sciences, and transplantation. Affiliated with the University of Toronto, UHN is a key player in the Toronto Academic Health Science Network, emphasizing innovation in medical research and education. Its renowned research institutes, such as the Krembil Research Institute and the Princess Margaret Cancer Centre, are internationally recognized for their medical contributions.