Popular Trials
PARP Inhibitor
Cediranib + Olaparib for Advanced Prostate Cancer
This trial looks at how well olaparib, with or without cediranib, works to treat patients with metastatic prostate cancer. Olaparib is a PARP inhibitor, which means it prevents PARP proteins from repairing DNA mutations. This may stop tumor cells from growing. Cediranib is an enzyme inhibitor that may also stop tumor cell growth.
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Trials for Prostate Cancer Patients
Hormone Therapy
Relugolix + Abiraterone Acetate vs Leuprolide + Abiraterone Acetate for Prostate Cancer
"This trial compares the effects of two different hormone therapies, leuprolide and abiraterone acetate, versus relugolix and abiraterone acetate on the heart in prostate
Chemotherapy
Opevesostat-Based Treatments for Prostate Cancer
This trial is a part of a larger study focusing on experimental treatments for advanced prostate cancer. The specific goal of this substudy is to assess the safety and effectiveness of using opevesostat alone
Radioisotope Therapy
Cu-SAR-bisPSMA for Prostate Cancer
This trial is testing a new radioactive treatment called 67Cu-SAR-bisPSMA in patients with advanced prostate cancer that has spread and does not respond to hormone treatments. The treatment works by sticking to cancer cells and using radioactivity to destroy them.
CAR T-cell Therapy
P-PSMA-101 CAR-T Cells for Prostate Cancer
This trial tests a treatment where a patient's immune cells are modified to better fight advanced prostate and salivary gland cancers. The modified cells are reintroduced into the body to target and destroy cancer cells.
Trials for Adenocarcinoma Patients
Hormone Therapy
Relugolix + Abiraterone Acetate vs Leuprolide + Abiraterone Acetate for Prostate Cancer
"This trial compares the effects of two different hormone therapies, leuprolide and abiraterone acetate, versus relugolix and abiraterone acetate on the heart in prostate
Chemotherapy
Opevesostat-Based Treatments for Prostate Cancer
This trial is a part of a larger study focusing on experimental treatments for advanced prostate cancer. The specific goal of this substudy is to assess the safety and effectiveness of using opevesostat alone
Radioisotope Therapy
Cu-SAR-bisPSMA for Prostate Cancer
This trial is testing a new radioactive treatment called 67Cu-SAR-bisPSMA in patients with advanced prostate cancer that has spread and does not respond to hormone treatments. The treatment works by sticking to cancer cells and using radioactivity to destroy them.
CAR T-cell Therapy
P-PSMA-101 CAR-T Cells for Prostate Cancer
This trial tests a treatment where a patient's immune cells are modified to better fight advanced prostate and salivary gland cancers. The modified cells are reintroduced into the body to target and destroy cancer cells.
Trials for Metastatic Patients
Chemotherapy
Opevesostat-Based Treatments for Prostate Cancer
This trial is a part of a larger study focusing on experimental treatments for advanced prostate cancer. The specific goal of this substudy is to assess the safety and effectiveness of using opevesostat alone
Radioisotope Therapy
Cu-SAR-bisPSMA for Prostate Cancer
This trial is testing a new radioactive treatment called 67Cu-SAR-bisPSMA in patients with advanced prostate cancer that has spread and does not respond to hormone treatments. The treatment works by sticking to cancer cells and using radioactivity to destroy them.
CAR T-cell Therapy
JNJ-78278343 for Prostate Cancer
This trial tests a new medicine that helps immune cells find and kill advanced prostate cancer cells. It is for patients whose cancer has spread and does not respond to usual treatments. The medicine works by linking immune cells to cancer cells, prompting an immune attack on the cancer.
Trials With No Placebo
Hormone Therapy
Relugolix + Abiraterone Acetate vs Leuprolide + Abiraterone Acetate for Prostate Cancer
"This trial compares the effects of two different hormone therapies, leuprolide and abiraterone acetate, versus relugolix and abiraterone acetate on the heart in prostate
Chemotherapy
Opevesostat-Based Treatments for Prostate Cancer
This trial is a part of a larger study focusing on experimental treatments for advanced prostate cancer. The specific goal of this substudy is to assess the safety and effectiveness of using opevesostat alone
Radioisotope Therapy
Cu-SAR-bisPSMA for Prostate Cancer
This trial is testing a new radioactive treatment called 67Cu-SAR-bisPSMA in patients with advanced prostate cancer that has spread and does not respond to hormone treatments. The treatment works by sticking to cancer cells and using radioactivity to destroy them.
CAR T-cell Therapy
P-PSMA-101 CAR-T Cells for Prostate Cancer
This trial tests a treatment where a patient's immune cells are modified to better fight advanced prostate and salivary gland cancers. The modified cells are reintroduced into the body to target and destroy cancer cells.
View More Related Trials
Frequently Asked Questions
Introduction to advanced prostate cancer
What are the top hospitals conducting advanced prostate cancer research?
In the quest to combat advanced prostate cancer, several hospitals have emerged as leaders in groundbreaking clinical trials. Memorial Sloan Kettering Cancer Center, located in the heart of New York City, is at the forefront with five ongoing trials dedicated to this challenging condition. While their all-time tally stands at only five trials thus far, it's important to note that they recorded their first trial as recently as 2018. The University of Wisconsin Carbone Cancer Center in Madison also plays a significant role in advancing prostate cancer research, with four active clinical trials currently underway. Although their history consists of just two completed trials, like Memorial Sloan Kettering, they too commenced their journey into exploring advanced prostate cancer treatments just a few years ago.
Meanwhile, researchers at the University of Chicago are actively engaged in four clinical trials for advanced prostate cancer. Although they do not have any past records specific to this disease yet, these ongoing studies show promising dedication and commitment towards uncovering new treatment options for patients facing this condition.
Dana-Farber Cancer Institute in Boston has made notable progress through its three active clinical trials focused on advanced prostate cancer. Their all-time count reaches up to four completed studies since launching their inaugural trial back in 2017; an impressive feat considering relatively recent engagement with this complex disease.
Lastly Massachusetts General Hospital based out of Boston also showcases immense dedication by conducting three current experimental tests despite having started researching about such cases quite later than others around 2019.Though lesser compared to other institutions on paper but make no mistake- multiple breakthroughs can be expected from here soon!
These leading hospitals serve as beacons of hope for individuals battling advanced prostate cancer while reaffirming our collective commitment towards finding better solutions and ultimately improving patient outcomes worldwide
Which are the best cities for advanced prostate cancer clinical trials?
When it comes to advanced prostate cancer clinical trials, several cities emerge as hubs of research and innovation. New york leads the way with 16 ongoing trials investigating treatments such as Docetaxel, JNJ-78278343, and TVB-2640 in combination with Enzalutamide. Boston closely follows with 13 active studies focusing on interventions like Cediranib, P-PSMA-101 CAR-T cells, and CPI-0209. Chicago also plays a significant role with 12 trials exploring therapies including Part 2 (Dose Expansion), T-CBSM, and Docetaxel. Additionally, Baltimore contributes to the advancement of prostate cancer care through its involvement in ten current trials examining approaches like Pelvic DCFPyL PET-MRI fusion or PET/MRI and 67Cu-SAR-bisPSMA. Lastly, Los Angeles conducts nine active trials studying various treatments such as Apalutamide and Peposertib alongside Docetaxel. These cities serve as beacons of hope for individuals battling advanced prostate cancer by providing access to cutting-edge clinical trials that pave the way for improved outcomes in their fight against this disease.
Which are the top treatments for advanced prostate cancer being explored in clinical trials?
The quest for effective treatments against advanced prostate cancer has led researchers to explore various options in clinical trials. Two standout contenders are docetaxel and 67Cu-SAR-bisPSMA. Docetaxel, introduced in 2020, is currently being tested in one active trial specifically targeting advanced prostate cancer among its three all-time trials. Meanwhile, the newly listed 67Cu-SAR-bisPSMA shows promise with one ongoing trial solely dedicated to advanced prostate cancer out of its total of one all-time trial since its introduction in 2021. These innovative therapies offer hope as scientists strive to find breakthrough solutions for those battling this challenging disease.
What are the most recent clinical trials for advanced prostate cancer?
Exciting developments are underway in the field of advanced prostate cancer treatment, with several recent clinical trials offering hope and potential advancements. Notably, an extended course of Sipuleucel-T has shown promise as a treatment option for individuals with advanced prostate cancer. Additionally, studies have explored dose escalation strategies to optimize outcomes for patients at different stages of the disease. Combination therapies such as TVB-2640 in conjunction with Enzalutamide have also been investigated, aiming to enhance the effectiveness of existing treatments. Furthermore, ongoing research continues to evaluate the efficacy and safety profiles of Docetaxel and REGN4336 in addressing advanced prostate cancer. These exciting trials offer new possibilities for improved care and outcomes for those affected by this challenging condition
What advanced prostate cancer clinical trials were recently completed?
Recently completed clinical trials have brought encouraging developments in the field of advanced prostate cancer. In July 2020, a trial sponsored by Hoffmann-La Roche concluded its investigation into the potential of Ipatasertib as a treatment option. Similarly, in June 2018, Janssen Research & Development successfully completed a trial exploring Apalutamide 240 mg for managing this aggressive form of cancer. Furthermore, January 2017 saw the completion of a trial sponsored by Hoffmann-La Roche studying Atezolizumab and its impact on advanced prostate cancer patients. These advancements hold promise for improved therapies and outcomes in the fight against this challenging disease.