Topoisomerase II inhibitors
Chemotherapy for Acute Lymphoblastic Leukemia
Recruiting2 awardsPhase 3
Birmingham, Alabama
This trial will study combination chemotherapy in young patients with newly diagnosed B acute lymphoblastic leukemia that is likely to come back or spread, and in patients with Philadelphia chromosome (Ph)-like tyrosine kinase inhibitor (TKI) sensitive mutations.
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Trials for T-Cell Lymphoblastic Leukemia Patients
Topoisomerase I inhibitors
Chemotherapy Regimen for Acute Lymphoblastic Leukemia
Recruiting2 awardsPhase 3
Boston, Massachusetts
This trial is studying a new way to treat acute lymphoblastic leukemia (ALL). The new way involves using a new, updated set of risk factors to decide how strong the treatment will be and testing a new way of dosing a chemotherapy drug.
CAR T-cell Therapy
CAR T-Cell Therapy for Acute Lymphoblastic Leukemia
Recruiting1 awardPhase 1 & 2
Los Angeles, California
This trial is testing a new cancer treatment involving genetically modified cells from the patient's own body. The goal is to find the maximum tolerated dose and to determine efficacy.
Topoisomerase II inhibitors
IMRT + Chemotherapy + Stem Cell Transplant for Leukemia
Recruiting1 awardPhase 1 & 2
Duarte, California
This trial is giving IMRT with chemotherapy to patients with relapsed or refractory ALL or AML before a donor stem cell transplant. The aim is to find out the side effects of this treatment and the best dose of IMRT to give, as well as how well the IMRT and chemotherapy work in treating patients.
Trials for ALL Patients
Topoisomerase I inhibitors
Chemotherapy Regimen for Acute Lymphoblastic Leukemia
Recruiting2 awardsPhase 3
Boston, Massachusetts
This trial is studying a new way to treat acute lymphoblastic leukemia (ALL). The new way involves using a new, updated set of risk factors to decide how strong the treatment will be and testing a new way of dosing a chemotherapy drug.
CAR T-cell Therapy
CAR T-Cell Therapy for Acute Lymphoblastic Leukemia
Recruiting1 awardPhase 1 & 2
Los Angeles, California
This trial is testing a new cancer treatment involving genetically modified cells from the patient's own body. The goal is to find the maximum tolerated dose and to determine efficacy.
Trials for CD19 Positive Patients
CAR T-cell Therapy
CAR T-Cell Therapy for Acute Lymphoblastic Leukemia
Recruiting1 awardPhase 1 & 2
Los Angeles, California
This trial is testing a new cancer treatment involving genetically modified cells from the patient's own body. The goal is to find the maximum tolerated dose and to determine efficacy.
CAR T-cell Therapy
CAR T-cell Therapy for Acute Lymphoblastic Leukemia
Recruiting1 awardPhase 1 & 2
Calgary, Alberta
This trial involves using a patient's own immune cells, which are modified in a lab to better recognize and attack cancer cells. The target group is patients with certain types of cancers. The modified cells are reintroduced into the patient to help their immune system fight the cancer more effectively. This approach has shown promising results in treating these cancers.
Trials for Philadelphia Chromosome Positive Patients
Corticosteroid
Immunotherapy + Chemotherapy for Acute Lymphoblastic Leukemia
Recruiting3 awardsPhase 1 & 2
Houston, Texas
This trial tests a new treatment combining inotuzumab ozogamicin and chemotherapy for elderly patients with acute lymphoblastic leukemia. The drug targets and kills cancer cells, aiming to improve outcomes for those who can't undergo intensive therapy or have had a recurrence. The study will determine the appropriate dose and evaluate the treatment's effectiveness and side effects.
Monoclonal Antibodies
Blinatumomab + Chemotherapy/Dasatinib for Acute Lymphoblastic Leukemia
Recruiting1 awardPhase 2
Birmingham, Alabama
This trial is studying the side effects and efficacy of blinatumomab and combination chemotherapy or dasatinib and prednisone in treating older patients with acute lymphoblastic leukemia.
Phase 3 Trials
Topoisomerase I inhibitors
Chemotherapy Regimen for Acute Lymphoblastic Leukemia
Recruiting2 awardsPhase 3
Boston, Massachusetts
This trial is studying a new way to treat acute lymphoblastic leukemia (ALL). The new way involves using a new, updated set of risk factors to decide how strong the treatment will be and testing a new way of dosing a chemotherapy drug.
Trials With No Placebo
Topoisomerase I inhibitors
Chemotherapy Regimen for Acute Lymphoblastic Leukemia
Recruiting2 awardsPhase 3
Boston, Massachusetts
This trial is studying a new way to treat acute lymphoblastic leukemia (ALL). The new way involves using a new, updated set of risk factors to decide how strong the treatment will be and testing a new way of dosing a chemotherapy drug.
CAR T-cell Therapy
CAR T-Cell Therapy for Acute Lymphoblastic Leukemia
Recruiting1 awardPhase 1 & 2
Los Angeles, California
This trial is testing a new cancer treatment involving genetically modified cells from the patient's own body. The goal is to find the maximum tolerated dose and to determine efficacy.
Topoisomerase II inhibitors
IMRT + Chemotherapy + Stem Cell Transplant for Leukemia
Recruiting1 awardPhase 1 & 2
Duarte, California
This trial is giving IMRT with chemotherapy to patients with relapsed or refractory ALL or AML before a donor stem cell transplant. The aim is to find out the side effects of this treatment and the best dose of IMRT to give, as well as how well the IMRT and chemotherapy work in treating patients.
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.