Popular Trials
PTC857 for ALS
Recruiting0 awardsPhase 2
Orange, California
This trial is testing a new drug called PTC857 to see if it can help people with ALS. Participants will either receive PTC857 or a non-active substance. If they complete the initial treatment, they can continue taking PTC857 for an extended period to further assess its effects.
Stem Cell Therapy
CNS10-NPC-GDNF for ALS
Recruiting1 awardPhase 1
Los Angeles, California
This trial is testing the safety of placing special cells into the brains of ALS patients. These cells release a protein that helps brain cells stay alive and healthy. The study aims to see if this new treatment is safe for people.
Rho Kinase Inhibitor
Rho Kinase Inhibitor for ALS
Recruiting1 awardPhase 2
Phoenix, Arizona
This trial is testing a new drug called WP-0512 to see if it can help people with ALS. It targets patients who have had ALS symptoms for a few years and meet specific health criteria. The drug aims to slow down the progression of ALS symptoms.
Janus Kinase (JAK) Inhibitor
Baricitinib for Alzheimer's & ALS
Recruiting1 awardPhase 1 & 2
Fort Lauderdale, Florida
This trial tests baricitinib, a pill taken daily, in people with early signs of Alzheimer's or ALS, or those at risk. The goal is to see if it can reduce harmful inflammation in the brain. Participants will take the medication for several months to check if it reaches the brain and lowers inflammation. Baricitinib is used for the treatment of rheumatoid arthritis and has shown promising preliminary data for moderate-to-severe atopic dermatitis.
Popular Filters
Trials for ALS Patients
Antisense Oligonucleotide
ION363 for ALS
Recruiting1 awardPhase 3
La Jolla, California
This trial is testing a new drug called ION363 to help people with a specific genetic form of ALS (FUS-ALS). The study will see if the drug can help these patients live longer and maintain their abilities better. Participants will receive the drug for a period of time, then all will get the drug for an extended duration.
T-cell Therapy
RAPA-501 Therapy for ALS
Recruiting1 awardPhase 2 & 3
Boston, Massachusetts
This trial tests a new treatment for ALS using a patient's own immune cells that are modified to reduce inflammation. It targets ALS patients who have not progressed beyond certain limits. The goal is to see if this treatment is safe and effective.
Trials for Lou Gehrig's Disease Patients
ABBV-CLS-7262 for ALS
Recruiting0 awardsPhase 1
Fredericton, New Brunswick
This trial is testing a new drug called ABBV-CLS-7262 to see if it can help people with Amyotrophic Lateral Sclerosis (ALS). The study will have two parts: an initial short phase where some people get the drug, followed by a longer phase where everyone gets the drug. The goal is to see if the drug can protect nerve cells and slow down the disease.
LAM-002A for ALS
Recruiting0 awardsPhase 2
Fort Lauderdale, Florida
This trial is testing a medication called LAM-002A in adults with a specific genetic form of ALS. The goal is to see if the medication is safe and if it helps with the disease. Participants will take the medication and be monitored for any effects.
Mesenchymal Stem Cells
Stem Cell Therapy for ALS
Recruiting1 awardPhase 2
Scottsdale, Arizona
This trial will test the safety and efficacy of delivering MSCs to the CSF of people with ALS every 3 months for a total of 4 injections over 12 months. The goal of the study is to determine if this treatment is safe and can improve the subject's ALS symptoms.
Behavioural Intervention
Combined Respiratory Training for ALS
Recruiting1 award4 criteria
Fort Lauderdale, Florida
This trial aims to understand how a combination of lung volume recruitment and expiratory muscle strength training can improve cough strength, respiratory function, dyspnea, bulbar impairment, caregiver burden, and quality of life in patients with ALS.
Phase 3 Trials
Antisense Oligonucleotide
ION363 for ALS
Recruiting1 awardPhase 3
La Jolla, California
This trial is testing a new drug called ION363 to help people with a specific genetic form of ALS (FUS-ALS). The study will see if the drug can help these patients live longer and maintain their abilities better. Participants will receive the drug for a period of time, then all will get the drug for an extended duration.
T-cell Therapy
RAPA-501 Therapy for ALS
Recruiting1 awardPhase 2 & 3
Boston, Massachusetts
This trial tests a new treatment for ALS using a patient's own immune cells that are modified to reduce inflammation. It targets ALS patients who have not progressed beyond certain limits. The goal is to see if this treatment is safe and effective.
Antisense Oligonucleotide
Tofersen for ALS
Recruiting1 awardPhase 3
Scottsdale, Arizona
This trial is testing a medication called tofersen in adults who have a genetic mutation that can lead to ALS, a serious nerve disease. These individuals show early signs of nerve damage. Tofersen works by lowering harmful proteins in the body to protect nerves and potentially delay or prevent the disease.
Trials With No Placebo
T-cell Therapy
RAPA-501 Therapy for ALS
Recruiting1 awardPhase 2 & 3
Boston, Massachusetts
This trial tests a new treatment for ALS using a patient's own immune cells that are modified to reduce inflammation. It targets ALS patients who have not progressed beyond certain limits. The goal is to see if this treatment is safe and effective.
Cannabinoid
Medical Cannabis for Chronic Pain
Recruiting1 awardPhase 2
Boca Raton, Florida
This trial will investigate if medical cannabis can effectively reduce pain and improve quality of life for patients with chronic conditions. The study will gather data through an online questionnaire about patients' use of cannabis and its effects. Medical cannabis interacts with the body's natural system to help manage pain and other symptoms. Medical cannabis has been increasingly studied and used as an alternative treatment for managing chronic pain, with numerous studies supporting its potential benefits.
Neurostimulation Device
Implantation of brain-computer interface for communication in ALS, quadriplegia, and Locked In Syndrome
Recruiting1 award6 criteria
Baltimore, Maryland
This trial will test a brain-computer interface that consists of platinum grids being implanted in the brain to pick up neural signals. Up to 128 channels will be used to test this interface for six months.
View More Related Trials
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.