Cannabinoid
Cannabis for Cancer-Related Symptoms
Recruiting0 awardsPhase 2
Vancouver, British Columbia
This trial will test the effectiveness of three cannabis oil extract combinations (High THC-Low CBD, Low THC-High CBD, or Equal amounts of THC and CBD) in a minimum of 120 cancer patients on 4 cancer-related symptoms: nausea, pain, anxiety and sleep disturbance.
Cannabinoid
Cannabidiol for Dementia
Recruiting0 awardsPhase 2
Aurora, Colorado
The major purpose of this study is to assess the efficacy of CBD on motor symptoms of Parkinson's Disease (PD), and secondarily to study the safety and tolerability of CBD and other efficacy, particularly regarding tremor in PD. The study has been powered to detect a clinically significant reduction in Movement Disorder Society (MDS) Unified Parkinson's Disease Rating Scale (UPDRS) Part III motor scores. This is a 1:1 parallel, double-blind, randomized controlled trial (RCT) with 60 participants. The investigators will be recruiting up to 75 participants; the goal is to have 60 participants (30 in CBD group and 30 in placebo group) complete the study. The study drug is obtained from the National Institute on Drug Abuse (NIDA).
Cannabinoid
CBD + THC for Chronic Pain
Recruiting0 awardsPhase < 1
Salt Lake City, Utah
This trial is testing THC and CBD on people with chronic non-cancer pain. THC can help reduce pain by affecting brain areas that process pain signals, while CBD may help by reducing inflammation and interacting with pain receptors. THC and CBD have been studied for their potential to manage chronic pain, with THC showing effectiveness in reducing pain signals and CBD being noted for its anti-inflammatory properties.
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Phase 3 Trials
Cannabinoid
CBD for Endometriosis Pain
Recruiting1 awardPhase 3
Hershey, Pennsylvania
This trial is testing CBD to see if it can help reduce pain and improve the quality of life for patients with endometriosis. The study will compare different doses of CBD over a few months. Researchers believe CBD may work by affecting the body's natural systems that control pain and inflammation. CBD has been shown to significantly improve pain intensity in some studies, although evidence quality is low due to high risk of bias and small sample sizes.
Cannabinoid
Cannabidiol for Autism
Recruiting0 awardsPhase 2 & 3
La Jolla, California
This trial is testing whether a medicine called cannabidiol (CBD) can help boys aged 7-14 with autism who have severe behavior problems. CBD, which comes from the cannabis plant but doesn't make you feel 'high,' might help by calming brain activity. The goal is to see if this treatment can improve their behavior and quality of life. Cannabidiol (CBD) has been reported to be safe and well-tolerated and has shown potential in managing symptoms of autism.
Cannabidiol for Seizures
Recruiting2 awardsPhase 3
Little Rock, Arkansas
This trial tests a medication called GWP42003-P in children under 2 years old who have severe seizure disorders like TSC, LGS, or DS. The study will last over a year and will check if the medication is safe, how it moves through the body, and if it helps reduce seizures. These conditions often don't respond well to usual treatments, so new options are needed. Cannabidiol (pharmaceutical) is approved by the FDA for the treatment of seizures associated with DS, Lennox-Gastaut syndrome, and tuberous sclerosis complex in patients ≥1 year of age.
Trials With No Placebo
Cannabidiol for Seizures
Recruiting2 awardsPhase 3
Little Rock, Arkansas
This trial tests a medication called GWP42003-P in children under 2 years old who have severe seizure disorders like TSC, LGS, or DS. The study will last over a year and will check if the medication is safe, how it moves through the body, and if it helps reduce seizures. These conditions often don't respond well to usual treatments, so new options are needed. Cannabidiol (pharmaceutical) is approved by the FDA for the treatment of seizures associated with DS, Lennox-Gastaut syndrome, and tuberous sclerosis complex in patients ≥1 year of age.
Cannabinoid
Cannabidiol for Obsessive-Compulsive Disorder
Recruiting1 awardPhase 2
Chicago, Illinois
This trial aims to test if Epidiolex can safely and effectively reduce symptoms in adults with obsessive-compulsive and related disorders by calming the brain and reducing anxiety. Epidiolex is a plant-derived pharmaceutical formulation of highly purified cannabidiol (CBD) that has been previously studied for its potential to be misused.
Trials Offering Remuneration
Cannabinoid
CBD for Autism
Recruiting0 awardsPhase 1
Baltimore, Maryland
This trial is testing if cannabidiol (CBD) can help with anxiety, mood issues, sleep problems, and agitation in adults with autism spectrum disorder (ASD). Participants will take CBD pills for a period of time. The study aims to see if CBD is effective and safe for these psychiatric problems. Cannabidiol (CBD) has shown promise in treating psychotic symptoms and anxiety, but there is not enough high-quality evidence for its clinical use in psychiatric disorders.
Cannabinoid
Cannabidiol + Tacrolimus for Transplant Rejection
Recruiting1 awardPhase 1
Indianapolis, Indiana
This trial aims to understand how CBD, a cannabis compound, interacts with tacrolimus, a drug used by organ transplant patients to prevent rejection. Researchers will study these interactions to see if CBD affects the safety and effectiveness of tacrolimus. Tacrolimus is a strong medication used to prevent organ rejection in transplant patients, with precise dosing requirements. The goal is to help doctors adjust doses of both substances to improve patient health and long-term treatment success.
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.