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Trials for CF Patients
Monoclonal Antibodies
Denosumab for Osteoporosis in Cystic Fibrosis
Recruiting3 awardsPhase 4
Dallas, Texas
This trial is testing a new way to treat CF patients with bone disease. Up to 100 subjects with CF will participate in a single study visit that will include a DEXA scan, micro CT, and blood collection. If results indicate bone disease, subjects will receive treatment with Denosumab for up to 5 years.
Cephalosporin Antibiotic
Ceftaroline for Cystic Fibrosis
Recruiting3 awardsPhase 4
Cincinnati, Ohio
This trial is testing a new way to give the antibiotic ceftaroline to kids with cystic fibrosis who also have a history of methicillin-resistant Staphylococcus aureus (MRSA), also known as oxacillin-resistant Staphylococcus aureus (ORSA).
Procedure
Glycine Buffer for Airway pH Measurement in Asthma
Recruiting1 awardPhase 1 & 2
Indianapolis, Indiana
This trial is testing a new way to measure airway pH in people with asthma and cystic fibrosis, using a new inhaled drug. The airway pH will help doctors tailor treatment plans for these conditions.
Trials for Cystic Fibrosis Liver Disease Patients
Monoclonal Antibodies
Denosumab for Osteoporosis in Cystic Fibrosis
Recruiting3 awardsPhase 4
Dallas, Texas
This trial is testing a new way to treat CF patients with bone disease. Up to 100 subjects with CF will participate in a single study visit that will include a DEXA scan, micro CT, and blood collection. If results indicate bone disease, subjects will receive treatment with Denosumab for up to 5 years.
Cephalosporin Antibiotic
Ceftaroline for Cystic Fibrosis
Recruiting3 awardsPhase 4
Cincinnati, Ohio
This trial is testing a new way to give the antibiotic ceftaroline to kids with cystic fibrosis who also have a history of methicillin-resistant Staphylococcus aureus (MRSA), also known as oxacillin-resistant Staphylococcus aureus (ORSA).
Procedure
Glycine Buffer for Airway pH Measurement in Asthma
Recruiting1 awardPhase 1 & 2
Indianapolis, Indiana
This trial is testing a new way to measure airway pH in people with asthma and cystic fibrosis, using a new inhaled drug. The airway pH will help doctors tailor treatment plans for these conditions.
Trials for CFTR Positive Patients
Procedure
Glycine Buffer for Airway pH Measurement in Asthma
Recruiting1 awardPhase 1 & 2
Indianapolis, Indiana
This trial is testing a new way to measure airway pH in people with asthma and cystic fibrosis, using a new inhaled drug. The airway pH will help doctors tailor treatment plans for these conditions.
Angiotensin II Receptor Blocker
Losartan for Cystic Fibrosis
Recruiting1 awardPhase < 1
Kansas City, Kansas
This trial is testing losartan, a blood pressure medication, to see if it can help clear mucus from the lungs of cystic fibrosis patients who can't use current treatments. These patients need alternative treatments because they don't respond to existing options. Losartan may reduce lung inflammation, making it easier for them to breathe.
GLP-1 Agonist
GLP-1 Agonist Therapy for Cystic Fibrosis-related Diabetes
Recruiting1 awardPhase 2
Philadelphia, Pennsylvania
This trial looks at whether a weekly injection of a medication called dulaglutide can help improve early-phase insulin secretion and glucose tolerance in people with cystic fibrosis-related diabetes.
Phase 3 Trials
Antibiotics for Cystic Fibrosis
Recruiting1 awardPhase 3
Vancouver, British Columbia
This trial tests if the antibiotic Cephalexin can help children with cystic fibrosis and a specific bacterial infection (MSSA) by improving their lung function. Cephalexin has been used in previous studies for antistaphylococcal prophylaxis in infants and young children with cystic fibrosis.
CFTR Modulator
VX-121 + Tezacaftor + Deutivacaftor for Cystic Fibrosis
Recruiting2 awardsPhase 3
Aurora, Colorado
This trial tests a combination of three drugs for cystic fibrosis patients with a specific genetic mutation. The drugs work together to fix the faulty protein in their cells, helping their lungs and other organs function better. Trikafta is a combination of three drugs (elexacaftor, tezacaftor, and ivacaftor) that target the F508del mutation in the CFTR gene.
Antibiotic
Rifaximin for Bloating in Cystic Fibrosis
Recruiting0 awardsPhase 2 & 3
Winston-Salem, North Carolina
This trial is testing rifaximin, an antibiotic, to help people with cystic fibrosis who have gut symptoms like bloating. The antibiotic works by balancing gut bacteria to reduce discomfort. Rifaximin has been used to treat travelers' diarrhea and other conditions, and it has shown effectiveness in reducing symptoms of irritable bowel syndrome (IBS).
Trials With No Placebo
Monoclonal Antibodies
Denosumab for Osteoporosis in Cystic Fibrosis
Recruiting3 awardsPhase 4
Dallas, Texas
This trial is testing a new way to treat CF patients with bone disease. Up to 100 subjects with CF will participate in a single study visit that will include a DEXA scan, micro CT, and blood collection. If results indicate bone disease, subjects will receive treatment with Denosumab for up to 5 years.
Cephalosporin Antibiotic
Ceftaroline for Cystic Fibrosis
Recruiting3 awardsPhase 4
Cincinnati, Ohio
This trial is testing a new way to give the antibiotic ceftaroline to kids with cystic fibrosis who also have a history of methicillin-resistant Staphylococcus aureus (MRSA), also known as oxacillin-resistant Staphylococcus aureus (ORSA).
Procedure
Glycine Buffer for Airway pH Measurement in Asthma
Recruiting1 awardPhase 1 & 2
Indianapolis, Indiana
This trial is testing a new way to measure airway pH in people with asthma and cystic fibrosis, using a new inhaled drug. The airway pH will help doctors tailor treatment plans for these conditions.
Angiotensin II Receptor Blocker
Losartan for Cystic Fibrosis
Recruiting1 awardPhase < 1
Kansas City, Kansas
This trial is testing losartan, a blood pressure medication, to see if it can help clear mucus from the lungs of cystic fibrosis patients who can't use current treatments. These patients need alternative treatments because they don't respond to existing options. Losartan may reduce lung inflammation, making it easier for them to breathe.
View More Related Trials
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.