Trials in Philadelphia, Pennsylvania
Here are the top 10 medical studies for depression in Philadelphia, Pennsylvania
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Phase 3 Trials
Psychedelic
Psilocybin for Treatment-Resistant Depression
Recruiting1 awardPhase 3
Toms River, New Jersey
This trial is testing a new medication called COMP360 to help people with severe depression that hasn't improved with other treatments. The study involves adults aged 18 and older. Researchers want to see if a single dose of COMP360 can reduce depression symptoms when given with psychological support.
Lumateperone for Major Depressive Disorder
Recruiting1 awardPhase 3
Philadelphia, Pennsylvania
This trial is testing lumateperone, a medication that may help people with depression who haven't improved with other treatments. The study includes patients diagnosed with Major Depressive Disorder who haven't responded well to their current antidepressants. Lumateperone works by balancing brain chemicals that affect mood, potentially improving depressive symptoms.
Behavioural Intervention
NMRA-335140 for Depression
Recruiting1 awardPhase 3
Staten Island, New York
This trial is testing a new medication called NMRA-335140 to see if it can help people with severe depression. The study involves participants with Major Depressive Disorder and aims to find out if the medication can improve their mood by altering brain chemicals.
NMRA-335140 for Depression
Recruiting2 awardsPhase 3
Media, Pennsylvania
This trial is testing a new medication called NMRA-335140 to see if it helps people with major depressive disorder. It includes participants who have no safety concerns. The medication aims to improve mood by affecting brain chemicals.
Trials With No Placebo
Mobile App Intervention for Childhood-Onset Lupus
Recruiting1 award
Bronx, New York
This trial aims to see if a custom mobile app can help young people with lupus stay engaged in their medical care and manage depression. The study focuses on adolescents and young adults from the Bronx, ages 15-24. The app offers personalized support to help them keep up with health appointments and improve their mood.
Glutamate Modulator
Glutamatergic Modulation for Post-COVID Depression
Recruiting1 awardPhase 2
New York, New York
This trial tests a medication that adjusts a brain chemical called glutamate to help people with long-term COVID-19 effects who are experiencing depression. Many studies have recently been conducted to assess the antidepressant efficacy of glutamate modification in mood disorders. The goal is to see if this treatment can improve their mood and mental clarity. The study involves giving the medication through infusions over several weeks.
Behavioral Intervention
PRIME Program for Chronic Pain and Depression
Recruiting1 award6 criteria
Baltimore, Maryland
This trial aims to help older women with disabilities who experience chronic pain and depression. The intervention includes home visits and virtual group sessions to help participants reduce pain and improve mood.
Behavioural Intervention
Mindfulness-Based Neurofeedback for Depression
Recruiting1 award
New York, New York
This trial uses real-time brain scans to help depressed adolescents practice mindfulness and control their brain activity. It targets teens with major depression who don't respond well to current treatments. By seeing their brain activity live, they can reduce negative thinking patterns that worsen depression.
Behavioral Intervention
Emotion Regulation Therapy for Emotional Distress
Recruiting1 award
New York, New York
This trial tests an online therapy to help people in New York who worry a lot or criticize themselves. The therapy aims to teach skills for managing negative thoughts and emotions to reduce anxiety and depression.
Psychotherapy
Psychotherapy for Postpartum Depression
Recruiting1 award6 criteria
New York, New York
This trial tests a remote therapy called Engage & Connect for new mothers with postpartum depression. The therapy aims to reduce depression by encouraging social activities with significant others, helping mothers feel happier and less isolated.
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.