Trials in San Antonio, Texas
Here are the top 7 medical studies for depression in San Antonio, Texas
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Phase 3 Trials
Aticaprant for Depression
Recruiting1 awardPhase 3
Austin, Texas
This trial is testing aticaprant to see if it can help adults with major depressive disorder and anhedonia who haven't responded well to other antidepressants. Aticaprant works by blocking certain receptors in the brain to potentially improve depressive symptoms.
Pharmacotherapy
Cariprazine for Bipolar Disorder in Youth
Recruiting1 awardPhase 3
Austin, Texas
This trial is testing the safety and effectiveness of Cariprazine for treating depressive episodes in children and teenagers with bipolar I disorder. The goal is to find out if Cariprazine can help young people with this condition. Cariprazine is an atypical antipsychotic recently approved for the treatment of depressive episodes in adults with bipolar I disorder.
Neuromodulation
Accelerated Brain Stimulation for Depression
Recruiting0 awardsPhase 2 & 3
Austin, Texas
This trial tests a magnetic pulse therapy on adults with severe depression and suicidal thoughts. The therapy targets a specific brain area to change brain communication, aiming to reduce suicidal thoughts and improve mood.
Behavioural Intervention
Lumateperone for Pediatric Bipolar Depression
Recruiting1 awardPhase 3
Austin, Texas
"This trial is studying the effectiveness of a new treatment for children with bipolar disorder who are also experiencing major depressive episodes. The study is being conducted at multiple locations and will involve random assignment of participants to receive
Psychedelic Therapy
Psilocybin for Depression
Recruiting1 awardPhase 3
San Antonio, Texas
This trial is testing psilocybin, a substance from mushrooms, to see if it can help adults with depression who may not respond well to current treatments. Psilocybin works by affecting brain chemicals related to mood. Psilocybin has shown promise as a treatment for major depressive disorder and was designated as a breakthrough therapy by the FDA in 2019.
Trials With No Placebo
Selective Serotonin Reuptake Inhibitor
Sertraline for Depression
Recruiting3 awardsPhase 4
Austin, Texas
This trial aims to use brain scans to predict how well patients with major depression will respond to the antidepressant sertraline. Sertraline, one of the oldest antidepressants, remains the most effective treatment for depression. By identifying specific brain activity patterns, doctors hope to better tailor treatments for each patient, improving outcomes for those who may not respond to typical treatments.
Behavioural Intervention
Tele-Behavioral Activation + Fall Prevention for Depression
Recruiting1 award4 criteria
Austin, Texas
This trial will test the effectiveness of an integrated behavioral activation and fall prevention program delivered by tele-counselors and coaches to low-income homebound seniors. The program will be compared to similar programs delivered by telephone or in person, with the goal of improving access to depression treatment and fall prevention for growing numbers of low-income homebound seniors.
Behavioral Intervention
FIRST Psychotherapy for Youth Mental Health Issues
Recruiting1 award3 criteria
Austin, Texas
This trial will compare the effectiveness of a new transdiagnostic treatment against usual care outpatient psychotherapy, for youths' mental health outcomes. The new treatment is based on five principles of change, and one proposed mechanism of change is regulation of negative emotions.
Procedure
RE104 for Postpartum Depression
Recruiting1 awardPhase 2
San Antonio, Texas
This trial is testing whether a single injection of RE104 can help reduce depression in women who have moderate-to-severe postpartum depression. The goal is to see if this treatment works effectively. The exact way RE104 works isn't detailed, but it likely helps by affecting brain chemicals related to mood.
Behavioural Intervention
AXS-05 for Depression
Recruiting3 awardsPhase 4
San Antonio, Texas
This trial is testing AXS-05, a new medication, to see if it can prevent depression from returning in people who have already improved with it. The study focuses on those with major depressive disorder and aims to maintain their balanced brain chemicals to keep them feeling better. AXS-05 (a combination of dextromethorphan and bupropion) has shown positive results in previous trials for major depressive disorder.
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.